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Table 2 Fractional Clearance Rates and kinetic parameters of LDE radioactive lipid labels in the Type 2 Diabetes Mellitus (T2DM) and Control groups.

From: Removal from the plasma of the free and esterified forms of cholesterol and transfer of lipids to HDL in type 2 diabetes mellitus patients

 

T2DM

Control

P

 

(n = 15)

(n = 11)

 

FCR 14 C-CE (h-1)

0.07 ± 0.02

0.05 ± 0.01

0.02

 k 1.014 C-CE

0.30 ± 0.15

0.30 ± 0.26

0.91

 k 1.214 C-CE

0.90 ± 1.20

0.97 ± 1.44

0.44

 k 2.014 C-CE

0.05 ± 0.02

0.03 ± 0.01

0.02

FCR 3 H-C(h-1)

0.05 ± 0.02

0.05 ± 0.02

0.75

 k 1.03 H-C

0.88 ± 0.83

0.86 ± 0.63

0.88

 k 1.23 H-C

0.89 ± 1.02

0.90 ± 1.02

1.00

 k 2.03 H-C

0.02 ± 0.01

0.03 ± 0.02

1.00

  1. Data are express as mean ± SD. LDE, non-protein LDL-like nanoemulsion. 14 C- CE, 14 C-cholesteryl ester. 3 H-C, 3 H-cholesterol.
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Lipids in Health and Disease

ISSN: 1476-511X