From: Formulation and evaluation of chitosan solid lipid nanoparticles of carbamazepine
Functional group | Drug | SLN formulation | Physical mixture | Tristearin | Phospholipon 80 H |
---|---|---|---|---|---|
N-H stretch | 3464 cm-1 | 3444.8 cm-1 | 3464.15 cm-1 | Absent | Absent |
C = 0 stretch | 1677 cm-1 | 1635.64 cm-1 | 1678.07 cm-1 | Absent | Absent |
Aromatic C-H stretch | 3080.75 cm-1 | Absent | 2954.95 cm-1 | 2954.95 cm-1 | 2954.95 cm-1 |
C = C stretch | 1605 cm-1 | 1635.64,1558.48 cm-1 | 1604.77 cm-1 | Absent | Absent |
C≡N | 1384.89 cm-1 | 1373.32 cm-1 | 1384.89 cm-1 | Absent | Absent |
CHO aldehydic group | Absent | 1732.80 cm-1 | 1735.93 cm-1 | 1728.22 cm-1 | 1725.92 cm-1 |
Methylene C-H asym stretch | Absent | Absent | 2916.37 cm-1 | 2914.44 cm-1 | 2916.37 cm-1 |
Polymeric | Absent | 3444.87 cm-1 | 3280.92 cm-1 | Absent | 3398.57 cm-1 |
3377.26 cm-1 | |||||
O-H stretch | 3419.97 cm-1 | 3281.93 cm-1 |