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Table 1 FTIR interpretation of CBZ SLN comparative to pure drug physical mixture and polymers

From: Formulation and evaluation of chitosan solid lipid nanoparticles of carbamazepine

Functional group Drug SLN formulation Physical mixture Tristearin Phospholipon 80 H
N-H stretch 3464 cm-1 3444.8 cm-1 3464.15 cm-1 Absent Absent
C = 0 stretch 1677 cm-1 1635.64 cm-1 1678.07 cm-1 Absent Absent
Aromatic C-H stretch 3080.75 cm-1 Absent 2954.95 cm-1 2954.95 cm-1 2954.95 cm-1
C = C stretch 1605 cm-1 1635.64,1558.48 cm-1 1604.77 cm-1 Absent Absent
C≡N 1384.89 cm-1 1373.32 cm-1 1384.89 cm-1 Absent Absent
CHO aldehydic group Absent 1732.80 cm-1 1735.93 cm-1 1728.22 cm-1 1725.92 cm-1
Methylene C-H asym stretch Absent Absent 2916.37 cm-1 2914.44 cm-1 2916.37 cm-1
Polymeric Absent 3444.87 cm-1 3280.92 cm-1 Absent 3398.57 cm-1
      3377.26 cm-1
O-H stretch   3419.97 cm-1    3281.93 cm-1