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Table 5 Effect of a single dose administration of CBZ SLN on reducing the duration of epileptic phases in INH indused epileptic model

From: Formulation and evaluation of chitosan solid lipid nanoparticles of carbamazepine

INH Induced method Control (Mean ± SEM) (Min) Standard (Mean ± SEM) (Min) Test (Mean ± SEM) (Min) Significance
Time for onset of convulsions 28 ± 1.195 58.17 ± 6.676 135.0 ± 25.10 (P<0.05) significant