Skip to main content
Figure 5 | Lipids in Health and Disease

Figure 5

From: Inhibition of nitric oxide and inflammatory cytokines in LPS-stimulated murine macrophages by resveratrol, a potent proteasome inhibitor

Figure 5

Resveratrol, pterostilbene, morin hydrate, and quercetin inhibit production of NO by RAW 264.7 cells treated with LPS alone, or LPS plus interferon-γ (IFN-γ). NO levels were measured in supernatants of RAW 264.7 treated with resveratrol, pterostilbene, morin hydrate, nicotinic acid, quercetin (16 μM) or medium alone (control) for 1 h, then challenged with LPS (10 ng/well) alone, LPS + IFN-γ (10 ng + 50 U/well) or medium alone (negative control) for 36 h. Cell viability exceeded 95% for all treatments. Data are means ± SD, n = 3 per treatment, and triplicate analyses of each sample were performed. Values in a column not sharing a common symbol are significantly different at P < 0.05. CTL = Control (Medium + RAW 264.7 cells + 0.2% DMSO); Resv = Resveratrol; Pter = Pterostilbene; Mori = Morin hydrate; Nico = Nicotinic acid; Quer = Quercetin-HCL. Figure A = Actual Relative Luminescence Unit (RLU) values. Figure B = Percentages of actual RLU values compared to control.

Back to article page