Resveratrol, pterostilbene, morin hydrate, and quercetin inhibit NF-κB activation in LPS-stimulated HEK293T cells. Relative luminescence of an NF-κB reporter compared to a β-galactosidase reporter (control) was measured to determine the extent of NF-κB activation in HEK293T cells treated with resveratrol, pterostilbene, morin hydrate, quercetin (16 μM) or medium alone for 1 h, then challenged with LPS (5 ng/well) for 5 h. Cell viability was >95% in all the treatments. Data are means ± SD, n = 2 per treatment, and duplicate analyses of each sample were performed. Values in a column not sharing a common symbol are significantly different at P < 0.05. CTL = Control (Medium + HEK293T cells + 0.4% DMSO); Resv = Resveratrol; Pter = Pterostilbene; Mori = Morin hydrate; Quer = Quercetin-HCL. Data presented represent the percent inhibition of NF-κB activation compared to control.