(A) Western blot analysis of COX-2 in the frontal cortex of rats submitted to sham operation and to BCCAO/R, pre-treated either with the vehicle alone or with the E.O. (B) Relative levels of COX-2 expression with densitometric analysis of the gray levels expressed as a percentage of the optical density (O.D.) ratio of the COX-2-positive bands to the GAPDH-positive ones. Error bars depict standard deviation. Different letters denote significant differences (p < 0.05).