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Table 3 Changes from baseline to follow-up in subcutaneous adipose tissue gene expression

From: Functional changes in adipose tissue in a randomised controlled trial of physical activity

  Median percent change (IQR) PANCOVA
  Controla
n = 30
Interventiona
n = 21
 
CD68 0 (-39, 59) -16 (-32, 20) 0.17
CCL2 -11 (-25, 66) -17 (-39, 11) 0.11
IL-6 -31 (-56, 7)** -16 (-62, 30) 0.87
TNFα -11 (-57, 38) -16 (-45, 42) 0.97
Adiponectin -34 (-66, 64) +38 (-42, 59) 0.35
Leptin -20 (-54, 195) +107 (-15, 428) 0.019
CD36 -8 (-16, 9) -10 (-47, 18) 0.55
LPL -3 (35, 26) -24 (-43, 12) 0.44
PPARγ -9 (-31, 21) -11 (-28, 26) 0.30
11βHSD1 -4 (-29, 15) +3 (-31, 18) 0.57
SCD +18 (-49, 109) -62 (-74, 4) 0.08
CNR1 -25 (-70, 70) -4 (-66, 101) 0.80
CNR2 -30 (-83, 96) -9 (-73, 111) 0.94
  1. a Significant within-group changes indicated: **P < 0.01.
  2. Total number of individuals analysed varies slightly due to technical reasons.
  3. Only percent changes are reported since gene expression is quantified in arbitrary units, absolute quantification is not performed.
  4. 11βHSD1: 11β-hydroxysteroid dehydrogenase type 1; CCL2: monocyte chemoattractant protein 1 (MCP-1); CNR1: cannabinoid receptor 1; CNR2: cannabinoid receptor 2; IL-6: interleukin 6; IQR: interquartile range; LPL: lipoprotein lipase; TNFα: tumour necrosis factor α; PPARγ: peroxisome proliferator activated receptor gamma; SCD: stearoyl CoA desaturase.