From: MYLIP p.N342S polymorphism is not associated with lipid profile in the Brazilian population
General population | Genotypes | p value | ||
---|---|---|---|---|
(n= 1295, 100%) | GG (n= 547) | GA (n= 571) | AA (n= 177) | Â |
Total cholesterol (mg/dL) | 213 ± 42.9 | 215.7 ± 45.8 | 213.5 ± 41.1 | 0.56 |
LDL-C (mg/dL) | 142.3 ± 37.4 | 143.6 ± 40.8 | 140.9 ± 36.5 | 0.67 |
HDL-C (mg/dL) | 46.0 ± 13.0 | 45.5 ± 12.1 | 45.9 ± 12.7 | 0.77 |
Triglycerides (mg/dL) | 126.9 ± 87.1 | 141.3 ± 138.9 | 135.6 ± 95.2 | 0.10 |
Glycemia (mg/dL) | 105.0 ± 30.2 | 104.3 ± 30.0 | 101.2 ± 27.1 | 0.33 |
Systolic blood pressure (mmHg) | 129.0 ± 23.3a | 127.2 ± 21.3a,b | 123.7 ± 19.5b | 0.01 |
Diastolic blood pressure (mmHg) | 84.9 ± 14.6a | 83.9 ± 13.9a,b | 81.6 ± 11.8b | 0.02 |
Mean blood pressure (mmHg) | 99.5 ± 16.8a | 98.3 ± 15.5a,b | 95.6 ± 13.6b | 0.01 |
Pulse wave velocity (m/s) | 9.9 ± 2.3 | 9.9 ± 2.2 | 9.7 ± 1.9 | 0.15 |
Patients submitted to coronary angiography | Genotypes | p value | ||
(n= 1425, 100%) | GG (n= 545) | GA (n= 633) | AA (n= 247) | Â |
Total cholesterol (mg/dL) | 228.4 ± 48.7 | 232.5 ± 51.4 | 228.6 ± 50.2 | 0.39 |
LDL-C (mg/dL) | 148.1 ± 45.0 | 149.6 ± 41.3 | 147.5 ± 48.8 | 0.86 |
HDL-C (mg/dL) | 43.0 ± 12.4 | 42.4 ± 11.5 | 42.0 ± 11.4 | 0.64 |
Triglycerides (mg/dL) | 184.0 ± 124.6 | 182.3 ± 147.6 | 188.1 ± 147.7 | 0.87 |
Glycemia (mg/dL) | 128.0 ± 50.8 | 128.9 ± 61.0 | 130.9 ± 59.7 | 0.82 |
Systolic blood pressure (mmHg) | 152.7 ± 31.6 | 150.4 ± 35.8 | 143 ± 38.1 | 0.21 |
Diastolic blood pressure (mmHg) | 82.4 ± 17.0 | 82.4 ± 14.6 | 80.7 ± 13.1 | 0.78 |
Ejection fraction (%) | 59.1 ± 15.6 | 61.2 ± 14.6 | 57.4 ± 14.9 | 0.17 |
Extension score | 2.2 ± 1.7 | 2.2 ± 1.6 | 2.2 ± 1.5 | 0.89 |
Severity score | 1.6 ± 1.3 | 1.6 ± 1.2 | 1.7 ± 1.3 | 0.97 |