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Table 2 Biochemical, hemodynamic, and angiographic data according to MYLIP rs9370867 genotypes

From: MYLIP p.N342S polymorphism is not associated with lipid profile in the Brazilian population

General population

Genotypes

p value

(n= 1295, 100%)

GG (n= 547)

GA (n= 571)

AA (n= 177)

 

Total cholesterol (mg/dL)

213 ± 42.9

215.7 ± 45.8

213.5 ± 41.1

0.56

LDL-C (mg/dL)

142.3 ± 37.4

143.6 ± 40.8

140.9 ± 36.5

0.67

HDL-C (mg/dL)

46.0 ± 13.0

45.5 ± 12.1

45.9 ± 12.7

0.77

Triglycerides (mg/dL)

126.9 ± 87.1

141.3 ± 138.9

135.6 ± 95.2

0.10

Glycemia (mg/dL)

105.0 ± 30.2

104.3 ± 30.0

101.2 ± 27.1

0.33

Systolic blood pressure (mmHg)

129.0 ± 23.3a

127.2 ± 21.3a,b

123.7 ± 19.5b

0.01

Diastolic blood pressure (mmHg)

84.9 ± 14.6a

83.9 ± 13.9a,b

81.6 ± 11.8b

0.02

Mean blood pressure (mmHg)

99.5 ± 16.8a

98.3 ± 15.5a,b

95.6 ± 13.6b

0.01

Pulse wave velocity (m/s)

9.9 ± 2.3

9.9 ± 2.2

9.7 ± 1.9

0.15

Patients submitted to coronary angiography

Genotypes

p value

(n= 1425, 100%)

GG (n= 545)

GA (n= 633)

AA (n= 247)

 

Total cholesterol (mg/dL)

228.4 ± 48.7

232.5 ± 51.4

228.6 ± 50.2

0.39

LDL-C (mg/dL)

148.1 ± 45.0

149.6 ± 41.3

147.5 ± 48.8

0.86

HDL-C (mg/dL)

43.0 ± 12.4

42.4 ± 11.5

42.0 ± 11.4

0.64

Triglycerides (mg/dL)

184.0 ± 124.6

182.3 ± 147.6

188.1 ± 147.7

0.87

Glycemia (mg/dL)

128.0 ± 50.8

128.9 ± 61.0

130.9 ± 59.7

0.82

Systolic blood pressure (mmHg)

152.7 ± 31.6

150.4 ± 35.8

143 ± 38.1

0.21

Diastolic blood pressure (mmHg)

82.4 ± 17.0

82.4 ± 14.6

80.7 ± 13.1

0.78

Ejection fraction (%)

59.1 ± 15.6

61.2 ± 14.6

57.4 ± 14.9

0.17

Extension score

2.2 ± 1.7

2.2 ± 1.6

2.2 ± 1.5

0.89

Severity score

1.6 ± 1.3

1.6 ± 1.2

1.7 ± 1.3

0.97

  1. Continuous data are expressed as mean ± standard deviation.
  2. Values with different superscript letters are significantly different (Tukey’s post hoc test).
  3. HDL-C: high density lipoprotein; LDL-C: low density lipoprotein.
  4. Biochemical data, blood pressures, ejection fraction, and angiographic scores were adjusted for age, gender, and ethnicity.
  5. Pulse wave velocity data was adjusted for age, gender, mean blood pressure, and ethnicity.