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Table 1 The general characteristics and serum lipid levels between the normolipidemic an hyperlipidemic subjects

From: Sex-specific association of ACAT-1 rs1044925 SNP and serum lipid levels in the hypercholesterolemic subjects

Parameter

Normolipidemia

Hyperlipidemia

t(χ2)

P

Number

345

476

-

-

Male/female

154/191

224/252

0.472

0.492

Age (years)

42.50 ± 14.91

43.82 ± 15.26

-1.240

0.215

Body mass index (kg/m2)

22.30 ± 2.63

23.34 ± 3.36

-4.954

0.000

Systolic blood pressure (mmHg)

120.85 ± 15.84

124.74 ± 17.37

-3.331

0.001

Diastolic blood pressure (mmHg)

75.30 ± 9.99

78.98 ± 10.73

-5.045

0.000

Pulse pressure (mmHg)

45.57 ± 11.67

45.76 ± 11.81

-0.220

0.826

Cigarette smoking [n (%)]

    

   Nonsmoker

242(70.1)

336(70.6)

  

   < 20 cigarettes/day

37(10.7)

36(7.6)

2.968

0.227

   ≥20 cigarettes/day

66(19.1)

104(21.8)

  

Alcohol consumption [n (%)]

    

   Nondrinker

206(59.7)

290(60.9)

  

   < 25 g/day

119(34.5)

130(27.3)

11.146

0.004

   ≥ 25 g/day

20(5.8)

56(11.8)

  

Total cholesterol (mmol/L)

4.31 ± 0.59

5.60 ± 0.96

-23.796

0.000

Triglyceride (mmol/L)

0.89(0.42)

1.59(1.11)

-14.552

0.000

HDL-C (mmol/L)

1.89 ± 0.41

1.97 ± 0.58

-2.035

0.042

LDL-C (mmol/L)

2.37 ± 0.49

3.15 ± 0.87

-16.334

0.000

Apolipoprotein (Apo) AI (g/L)

1.41 ± 0.22

1.50 ± 0.31

-4.857

0.000

ApoB (g/L)

0.82 ± 0.15

1.05 ± 0.23

-16.887

0.000

ApoAI/ApoB

1.79 ± 0.56

1.51 ± 0.58

6.762

0.000

  1. HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol. The value of triglyceride was presented as median (interquartile range), the difference between the two groups was determined by the Wilcoxon-Mann-Whitney test.