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Table 5 Odds ratios (ORs) and 95% confidence intervals (CIs) for hypertriglyceridemia by Mt5178 C/A genotype and smoking status

From: Mitochondrial DNA 5178 C/A polymorphism influences the effects of habitual smoking on the risk of dyslipidemia in middle-aged Japanese men

Genotype and number of cigarette smoked daily

Frequency

OR (95% CI)

Adjusted OR† (95% CI)

Adjusted OR‡ (95% CI)

Normal triglyceride level(Triglyceride < 150 mg/dl)

Hypertriglyceridemia(Triglyceride ≥ 150 mg/dl)

Mt5178C

     

0 (never- or ex-smoker)

102 (71.8)

40 (28.2)

1 (reference)

1 (reference)

1 (reference)

1-20

48 (68.6)

22 (31.4)

1.169 (0.627-2.180)

1.226 (0.640-2.350)

1.355 (0.681-2.697)

>20

18 (66.7)

9 (33.3)

1.275 (0.529-3.073)

1.429 (0.563-3.631)

1.517 (0.575-3.998)

   

P for trend = 0.517

P for trend = 0.366

P for trend = 0.282

Mt5178A

     

0 (never- or ex-smoker)

70 (76.1)

22 (23.9)

1 (reference)

1 (reference)

1 (reference)

1-20

31 (77.5)

9 (22.5)

0.924 (0.382-2.234)

1.261 (0.485-3.284)

1.588 (0.537-4.697)

>20

8 (34.8)

15 (65.2)

5.966 (2.233-15.90)**

5.629 (2.071-15.30)**

6.397 (2.177-18.79)**

   

P for trend = 0.002

P for trend = 0.002

P for trend < 0.001

  1. †OR adjusted for age and body mass index.
  2. ‡OR adjusted for age, body mass index, habitual alcohol consumption, coffee consumption and antihypertensive medication.
  3. *P < 0.05, **P < 0.005.