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Table 1 Baseline demographics and clinical characteristics

From: Consistency of effect of ezetimibe/simvastatin compared with intensified lipid-lowering treatment strategies in obese and non-obese diabetic subjects

  EZ/Simva 10/20 mg Doubling statin dose Rosuvastatin 10 mg
Obese subjects n = 181 n = 93 n = 192
Sex, n (%)       
 Male 90 (49.7) 46 (49.5) 102 (53.1)
 Female 91 (50.3) 47 (50.5) 90 (46.9)
Age, years Mean (SD) 63.3 (8.2) 63.5 (8.5) 63.3 (8.2)
Weight, kg Mean (SD) 99.3 (15.3) 96.2 (12.5) 96.5 (13.3)
Body Mass Index (BMI, kg/m 2 )       
Mean (SD) 35.4 (4.3) 34.6 (3.7) 34.6 (3.7)
Race, n (%)       
 American Indian or Alaska Native 1 (0.6) 0 (0.0) 1 (0.5)
 Black or African American 4 (2.2) 1 (1.1) 1 (0.5)
 Multi-Racial 10 (5.5) 4 (4.3) 8 (4.2)
 White 166 (91.7) 88 (94.6) 182 (94.8)
Ethnicity, n (%)       
 Hispanic or Latino 19 (10.5) 9 (9.7) 22 (11.5)
 Not Hispanic or Latino 162 (89.5) 84 (90.3) 170 (88.5)
Clinical Characteristics, mg/dL Mean SD Mean SD Mean SD
LDL-C 97.9 22.4 99.3 22.0 95.7 19.1
Total cholesterol 179.0 30.4 180.5 27.0 178.3 24.2
Triglycerides* 149.0 74.4 136.0 77.2 143.5 74.4
HDL-C 48.6 11.5 51.0 11.6 47.8 10.7
Non-HDL-C 130.4 28.3 129.4 25.8 127.5 23.6
Apo B 101.6 19.8 101.7 17.7 100.0 18.6
Apo A-I 148.4 24.6 153.5 22.2 147.6 22.0
hs-CRP*, mg/L 2.4 2.9 1.9 3.2 2.6 3.7
Non-obese subjects n = 141 n = 69 n = 132
Sex, n (%)       
 Male 70 (49.6) 34 (49.3) 80 (60.6)
 Female 71 (50.4) 35 (50.7) 52 (39.4)
Age, years Mean (SD) 65.2 (9.3) 66.2 (7.9) 64.0 (8.6)
Weight, kg Mean (SD) 73.5 (11.0) 76.3 (11.5) 76.3 (11.5)
Body mass index (BMI, kg/m 2 )       
Mean (SD) 35.4 (4.3) 34.6 (3.7) 34.6 (3.7)
Race, n (%)       
 American Indian or Alaska Native 3 (2.1) 2 (2.9) 4 (3.0)
 Black or African American 1 (0.7) 1 (1.4) 1 (0.8)
 Multi-Racial 23 (16.3) 7 (10.1) 16 (12.1)
 White 114 (80.9) 59 (85.5) 111 (84.1)
Ethnicity, n (%)       
Hispanic or Latino 45 (31.9) 16 (23.2) 32 (24.2)
Not Hispanic or Latino 96 (68.1) 53 (76.8) 100 (75.8)
Clinical characteristics, mg/dL Mean SD Mean SD Mean SD
LDL-C 100.1 21.6 94.7 20.2 99.9 20.5
Total cholesterol 180.5 30.9 173.0 26.3 178.7 28.7
Triglycerides* 126.0 65.1 126.0 51.2 132.0 76.3
HDL-C 52.6 15.8 50.6 12.7 50.5 13.3
Non-HDL-C 127.9 26.9 122.4 25.3 128.2 26.4
Apo B 101.7 20.4 98.9 20.1 101.0 20.0
Apo A-I 152.7 32.9 153.1 28.2 149.4 27.3
hs-CRP*, mg/L 1.6 2.9 2.0 2.2 1.6 2.3
  1. *Data for TG and hs-CRP are presented as median and robust standard deviation.
  2. EZ Ezetimibe, Simva Simvastatin.