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Figure 6 | Lipids in Health and Disease

Figure 6

From: Saturated fatty acid palmitate-induced insulin resistance is accompanied with myotube loss and the impaired expression of health benefit myokine genes in C2C12 myotubes

Figure 6

The transcription of myokine genes differently responded to SB203580 and LY294002. C2C12 myotubes were treated with 0.4 mM palmitate with or without chemical inhibitors for 24 hours. The transcription of FNDC5 gene (A, B), CTRP15 gene (C, D), FGF21 gene (E, F) and IL6 gene (G, H) was measured by qRT-PCR and monitored via 18S as internal control. The values were expressed as meanĀ±SEM (n=3). *p<0.05, **p<0.01, ns, no significant. PA, 0.4 mM palmitate; SB, 10 uM SB203580; LY, 10 uM LY294002.

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