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Table 1 Circulating and mRNA expression levels of adipocyte-related molecules in WKY and SHRSP

From: Effects of Angiotensin II Type 1 receptor blocker and adiponectin on adipocyte dysfunction in stroke-prone spontaneously hypertensive rats

 

6 weeks of age

20 weeks of age

 

WKY

SHRSP

WKY

SHRSP

Serum adipokine levels

Leptin (ng/ml)

2.895±0.700

0.568±0.450

9.003±0.673

4.497±0.383**

Adiponectin (μg/ml)

11.559±1.037

8.491±0.243**

10.054±0.219

5.934±0.222**

Adipokine expression in epididymal adipocytes (ratio to 18S rRNA)

Leptin

1.059±0.098

0.251±0.049**

4.204±0.746

2.012±0.177**

Adiponectin

1.045±0.070

0.609±0.050*

1.301±0.108

1.167±0.05

PPARγ

1.010±0.086

0.544±0.068*

0.517±0.038

0.407±0.050

  1. SHRSP: stroke-prone spontaneously hypertensive rats; PPARγ: peroxisome proliferator-activated receptor γ; WKY: Wistar–Kyoto rats. Values are means ± SE. *p < 0.05 and **p < 0.01 vs. age matched WKY (Student’s t-test).