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Table 3 Association of each ADRB2 polymorphism with lipid traits

From: Association of ADRB2 polymorphism with triglyceride levels in Tongans

SNP Derived allele Frequency Total cholesterol (mg/dL) HDL cholesterol (mg/dL) LDL cholesterol (mg/dL) Triglyceride
(mg/dL) (mg/dL) (mg/dL) (mg/dL)
    β SE P-value β SE P-value β SE P-value β SE P-value
rs17778257 T 0.39 5.17 5.52 0.351 0.110 1.06 0.918 4.34 4.83 0.371 8.20 12.8 0.523
rs34623097 A 0.04 13.7 14.6 0.350 −2.88 2.78 0.302 3.60 12.8 0.779 70.1 33.3 0.037
rs2895795 A 0.52 −8.09 5.42 0.138 −0.0671 1.04 0.949 −6.18 4.75 0.196 −19.1 12.5 0.130
rs2053044 A 0.09 10.0 9.82 0.312 −0.128 1.88 0.946 6.35 8.61 0.462 36.3 22.6 0.111
rs11959427a T 0.95 −8.00 13.5 0.557 1.70 2.60 0.503 −3.50 11.9 0.768 −36.1 31.2 0.250
rs1042711 (Arg19Cys) T (Cys) 0.95 −7.97 13.5 0.557 1.74 2.58 0.503 −3.51 11.9 0.768 −36.1 31.2 0.250
rs1042713 (Gly16Arg)a A (Arg) 0.42 5.70 5.30 0.285 0.400 1.00 0.720 4.50 4.70 0.344 13.9 12.5 0.267
rs1042714 (Glu27Gln)a C (Gln) 0.96 −8.50 14.6 0.563 2.10 2.80 0.443 −5.20 12.8 0.683 −37.9 33.7 0.263
rs1042719 C 0.43 4.42 5.38 0.413 −0.102 1.03 0.921 2.30 4.72 0.627 23.7 12.3 0.057
rs1042720 A 0.61 −2.47 5.48 0.652 0.616 1.04 0.556 0.05 4.80 0.992 −23.8 12.5 0.059
  1. A multiple regression analysis adjusted for age, sex, and BMI was performed to examine the association of each polymorphism with each lipid trait; BMI Body Mass Index, HDL High Density Lipoprotein, LDL Low Density Lipoprotein.
  2. a The genotypes of subjects whose genotypes had not been determined by a molecular biology-based technique were imputed by using the MACH software.