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Figure 4 | Lipids in Health and Disease

Figure 4

From: Polyunsaturated fatty acid relatively decreases cholesterol content in THP-1 macrophage-derived foam cell: partly correlates with expression profile of CIDE and PAT members

Figure 4

Effects of PUFAs on cholesterol efflux to lipid-free apoAI or to HDL. THP-1 macrophages or monocyte-macrophages were pre-treated with different NEFA, and then incubated with ox-LDL containing 1 μCi/ml [3H] cholesterol and 2 mg/ml BSA. The radioactivity was measured by scintillation counting. Cholesterol efflux to apoAI from foam cells was increased in LA and EPA groups. PUFAs had no effect on cholesterol efflux to HDL from foam cells. Data represent mean ± SEM (n = 3). P < 0.05 vs. control.

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