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Table 1 Specific NEFA induced fold-changes of mRNAs

From: Polyunsaturated fatty acid relatively decreases cholesterol content in THP-1 macrophage-derived foam cell: partly correlates with expression profile of CIDE and PAT members

Protein

Control

PA

OA

LA

EPA

SR-A1

-0.25

-0.61*

1.12*

-1.30*#

-0.96*#

CD36

0.81

0.32

0.26

-1.03*

-0.67*

ABCA1

2.15

-0.36

-0.26

0.11

1.20*

ApoAI

1.15

2.82*

-4.73*

3.02*#

5.24*#

PPARγ

0.18

1.30*#

0.17

0.18

0.48*

Cidea

0.02

-1.54*

-3.87*

3.17*#

1.02#

Cideb

1.35

2.43*

1.67*

0.28#

0.17#

Cidec

0.65

-0.24

-0.27

0.84#

1.75*#

Perilipin

-0.15

-2.11*

-3.04*

2.42*

-0.24

ADRP

4.05

5.22*

4.36*

9.55*#

7.78*#

TIP47

0.99

1.39*

0.54*

-1.79*

2.04*#

S3-12

0.38

2.10*

-2.80*

6.30*#

3.21*#

LSDP5

1.03

1.60*

-2.02*

2.96*#

0.10

  1. Values were presented as: log2 (mRNA level in foam cell/mRNA level in macrophage).
  2. (*P < 0.05; #P < 0.05 vs. respective control).