Figure 1From: Decreased APOE-containing HDL subfractions and cholesterol efflux capacity of serum in mice lacking Pcsk9HDL cholesterol concentrations in control and Pcsk9 KO males and females. Plasma was obtained from male and female mice (n > 10 per genotype) fed a normal chow diet from weaning until 8 weeks of age and then an atherogenic diet until 16 weeks of age. Data represent the mean ± SEM. *P < 0.05, †P < 0.001, ‡P < 0.0001.Back to article page