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Figure 7 | Lipids in Health and Disease

Figure 7

From: Decreased APOE-containing HDL subfractions and cholesterol efflux capacity of serum in mice lacking Pcsk9

Figure 7

Atherosclerotic fatty streak volume in control and Pcsk9 KO mice. Control and Pcsk9 KO males (34-week-old; n = 5 per genotype) were fed an atherogenic diet for 10 weeks. Aortic sections were stained with oil-red O (A) and fatty streaks are indicated by arrows (A), 3D image was reconstructed (B) and the fatty streak volume (mm3) quantified in 240 μm of aortic sinus (C). Data represent the mean ± SEM.

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