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Table 2 Changes of body weight and serum lipid levels after six and ten weeks in different groups (mean± SD, n=6)

From: The anti-inflammatory effect of kaempferol on early atherosclerosis in high cholesterol fed rabbits

 

Control

Model

Fenofibrate

Kaempferol-H

Kaempferol-L

Bodyweight (kg)

     

Week 6

2.49 ± 0.22

2.82 ± 0.36

2.65 ± 0.24

2.68 ± 0.28

2.66 ± 0.25

Week 10

2.93 ± 0.15

3.24 ± 0.40

3.15 ± 0.33

3.10 ± 0.13

3.09 ± 0.24

TC (mmol/L)

     

Week 6

1.13 ± 0.33

6.01 ± 2.48##

2.43 ± 0.57**

1.52 ± 0.24**

2.74 ± 0.83**

Week 10

1.11 ± 0.24

9.36 ± 3.96##

4.26 ± 1.44**

2.97 ± 1.41**

3.70 ± 1.14**

TG (mmol/L)

     

Week 6

0.58 ± 0.16

1.80 ± 0.47##

1.09 ± 0.32**

0.85 ± 0.10**

0.88 ± 0.27**

Week 10

0.62 ± 0.1

2.26 ± 0.82##

0.88 ± 0.14**

1.39 ± 0.63*

1.30 ± 0.42*

HDL-C (mmol/L)

     

Week 6

0.65 ± 0.09

1.92 ± 0.57##

1.04 ± 0.24**

0.83 ± 0.16**

1.04 ± 0.21**

Week 10

0.68 ± 0.14

2.51 ± 0.74##

1.76 ± 0.67*

1.29 ± 0.57**

1.64 ± 0.37*

LDL-C (mmol/L)

     

Week 6

0.44 ± 0.13

3.21 ± 1.85##

1.07 ± 0.12**

0.62 ± 0.20**

1.24 ± 0.48*

Week 10

0.46 ± 0.13

3.79 ± 2.20##

1.76 ± 0.50**

1.07 ± 0.61**

1.69 ± 0.86*

  1. Control: rabbits fed on normal diets; Model: rabbits fed on high-cholesterol diets; Fenofibrate: rabbits received high-cholesterol diets plus fenofibrate (12 mg/kg); Kaempferol-H: rabbits received high-cholesterol diets plus kaempferol (150 mg/kg); Kaempferol-L: rabbits received high-cholesterol diets plus kaempferol (30 mg/kg). TC: total cholesterol; TG: triglyceride; HDL-C: high density lipoprotein cholesterol; LDL-C: low density lipoprotein cholesterol. *P<0.05, **p < 0.01, compared with model group; ## p < 0.01, compared with control group.