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Table 2 Fatty acid composition of erythrocyte membranes in patients with chronic respiratory diseases, mean ± SE

From: Modification of the fatty acid composition of the erythrocyte membrane in patients with chronic respiratory diseases

Fatty acids % Healthy subjects n = 10 Patient with chronic bronchitis n = 15 Patients with chronic obstructive pulmonary disease n = 15
12:0 0.18 ± 0.01 0.35 ± 0.07**  
14:0 0.39 ± 0.03 0.65 ± 0.12** ×××0.34 ± 0.01
15:0 0.17 ± 0.01 0.24 ± 0.04* ×××1.08 ± 0.01***
16:0 23.98 ± 1.28 22.32 ± 1.47 23.16 ± 0.28
16:1n-9 0.21 ± 0.05 0.27 ± 0.03 0.21 ± 0.05
16:1n-7 0.39 ± 0.03 0.51 ± 0.05* 0.53 ± 0.05
17:0 0.35 ± 0.02 0.27 ± 0.03 0.25 ± 0.03
18:0 13.40 ± 0.75 15.27 ± 0.52 16.78 ± 0.40*
18:1n-9 14.84 ± 0.84 14.86 ± 0.45 15.49 ± 0.73
18:1n-7 1.53 ± 0.08 1.33 ± 0.12 ××1.76 ± 0.05
18:1n-5 0.32 ± 0.02 0.33 ± 0.08 0.36 ± 0.14
18:2n-6 15.75 ± 0.28 15.00 ± 0.16 ×××12.21 ± 0.61**
18:3n-3 0.15 ± 0.02 0.22 ± 0.09 ×××0.13 ± 0.03
20:0 0.15 ± 0.035 0.13 ± 0.04 ×××0.46 ± 0.04***
20:1 0.34 ± 0.07 0.27 ± 0.07 0.23 ± 0.03
20:2n-6 0.25 ± 0.005 0.29 ± 0.03 0.26 ± 0.02
20:3n-6 1.59 ± 0.51 1.45 ± 0.17 1.70 ± 0.20
20:4n-6 12.95 ± 1.65 14.89 ± 0.79* ×××18.26 ± 0.50***
20:5n-3 1.23 ± 0.04 0.93 ± 0.09* ×××0.56 ± 0.06***
22:4n-6 2.37 ± 0.29 2.38 ± 0.22 ×3.18 ± 0.31**
22:5n-6 0.37 ± 0.01 0.31 ± 0.04 ×0.46 ± 0.07
22:5n-3 1.99 ± 0.02 1.88 ± 0.03* 1.82 ± 0.05*
22:6n-3 4.67 ± 0.85 6.09 ± 0.60 5.87 ± 0.39
Sum n-6 32.91 ± 0.10 34.32 ± 0.70* 36.07 ± 0.55**
Sum n-3 8.04 ± 0.12 9.12 ± 0.89 8.32 ± 0.42
20:4n-6/20:5n-3 10.52 ± 0.12 16.01 ± 1.3*** 32.60 ± 2.8***
  1. Other fatty acids (10:0, 19:0, 22:0, 14:1, 22:1, 18:2n-5/9, and 20:3n-3) were present in trace amounts (< 0.1%) and are not included into the table.
  2. Asteriks indicate significant differences of fatty acid contents between patients with respiratory diseases and healthy subjects: * for р < 0.05; ** for р < 0.01; *** for р < 0.001; Asteriks indicate significant differences of fatty acid contents between patients with chronic bronchitis and with chronic obstructive pulmonary disease: × for р < 0.05; ×× for р < 0.01; ××× for р < 0.001.