|
Fatty acids %
|
Healthy subjects n = 10
|
Patient with chronic bronchitis n = 15
|
Patients with chronic obstructive pulmonary disease n = 15
|
|---|
|
12:0
|
0.18 ± 0.01
|
0.35 ± 0.07**
| |
|
14:0
|
0.39 ± 0.03
|
0.65 ± 0.12**
|
×××0.34 ± 0.01
|
|
15:0
|
0.17 ± 0.01
|
0.24 ± 0.04*
|
×××1.08 ± 0.01***
|
|
16:0
|
23.98 ± 1.28
|
22.32 ± 1.47
|
23.16 ± 0.28
|
|
16:1n-9
|
0.21 ± 0.05
|
0.27 ± 0.03
|
0.21 ± 0.05
|
|
16:1n-7
|
0.39 ± 0.03
|
0.51 ± 0.05*
|
0.53 ± 0.05
|
|
17:0
|
0.35 ± 0.02
|
0.27 ± 0.03
|
0.25 ± 0.03
|
|
18:0
|
13.40 ± 0.75
|
15.27 ± 0.52
|
16.78 ± 0.40*
|
|
18:1n-9
|
14.84 ± 0.84
|
14.86 ± 0.45
|
15.49 ± 0.73
|
|
18:1n-7
|
1.53 ± 0.08
|
1.33 ± 0.12
|
××1.76 ± 0.05
|
|
18:1n-5
|
0.32 ± 0.02
|
0.33 ± 0.08
|
0.36 ± 0.14
|
|
18:2n-6
|
15.75 ± 0.28
|
15.00 ± 0.16
|
×××12.21 ± 0.61**
|
|
18:3n-3
|
0.15 ± 0.02
|
0.22 ± 0.09
|
×××0.13 ± 0.03
|
|
20:0
|
0.15 ± 0.035
|
0.13 ± 0.04
|
×××0.46 ± 0.04***
|
|
20:1
|
0.34 ± 0.07
|
0.27 ± 0.07
|
0.23 ± 0.03
|
|
20:2n-6
|
0.25 ± 0.005
|
0.29 ± 0.03
|
0.26 ± 0.02
|
|
20:3n-6
|
1.59 ± 0.51
|
1.45 ± 0.17
|
1.70 ± 0.20
|
|
20:4n-6
|
12.95 ± 1.65
|
14.89 ± 0.79*
|
×××18.26 ± 0.50***
|
|
20:5n-3
|
1.23 ± 0.04
|
0.93 ± 0.09*
|
×××0.56 ± 0.06***
|
|
22:4n-6
|
2.37 ± 0.29
|
2.38 ± 0.22
|
×3.18 ± 0.31**
|
|
22:5n-6
|
0.37 ± 0.01
|
0.31 ± 0.04
|
×0.46 ± 0.07
|
|
22:5n-3
|
1.99 ± 0.02
|
1.88 ± 0.03*
|
1.82 ± 0.05*
|
|
22:6n-3
|
4.67 ± 0.85
|
6.09 ± 0.60
|
5.87 ± 0.39
|
|
Sum n-6
|
32.91 ± 0.10
|
34.32 ± 0.70*
|
36.07 ± 0.55**
|
|
Sum n-3
|
8.04 ± 0.12
|
9.12 ± 0.89
|
8.32 ± 0.42
|
|
20:4n-6/20:5n-3
|
10.52 ± 0.12
|
16.01 ± 1.3***
|
32.60 ± 2.8***
|
- Other fatty acids (10:0, 19:0, 22:0, 14:1, 22:1, 18:2n-5/9, and 20:3n-3) were present in trace amounts (< 0.1%) and are not included into the table.
- Asteriks indicate significant differences of fatty acid contents between patients with respiratory diseases and healthy subjects: * for р < 0.05; ** for р < 0.01; *** for р < 0.001; Asteriks indicate significant differences of fatty acid contents between patients with chronic bronchitis and with chronic obstructive pulmonary disease: × for р < 0.05; ×× for р < 0.01; ××× for р < 0.001.
