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Table 2 Effect of dietary CBAG leaf on growth and serum parameters in mice

From: Cirsium brevicaule A. GRAY leaf inhibits adipogenesis in 3T3-L1 cells and C57BL/6 mice

Parameters

Group

 

Control diet

5% CL diet

10% CL diet

Food Intake (g/day)

2.25 ± 0.01

2.22 ± 0.04

2.24 ± 0.03

Initial body weight (g)

13.9 ± 0.32

13.7 ± 0.27

13.7 ± 0.28

Final body weight (g)

25.7 ± 0.43

24.8 ± 0.54

24.5 ± 0.40

Liver weight (g/100 g body weight)

4.50 ± 0.11

3.88 ± 0.17*

3.67 ± 0.12**

White adipose tissue weight (g/100 g body weight)

  

Total†

6.03 ± 0.47

5.75 ± 0.36

5.26 ± 0.28

Abdominal§

4.34 ± 0.35

4.36 ± 0.31

4.00 ± 0.22

Epididymal

2.18 ± 0.16

2.13 ± 0.16

1.98 ± 0.11

Perirenal

0.81 ± 0.14

0.80 ± 0.07

0.64 ± 0.06

Omental

1.35 ± 0.08

1.44 ± 0.10

1.37 ± 0.08

Subcutaneous

1.69 ± 0.12

1.39 ± 0.06

1.26 ± 0.08**

Serum parameters

   

Triglyceride (mg/dL)

35.0 ± 3.41

40.5 ± 3.71

32.2 ± 3.10

Total cholesterol (mg/dL)

107 ± 4

107 ± 4

114 ± 3

Non-esterified fatty acid (mEq/dL)

9.68 ± 0.89

8.41 ± 0.40

6.56 ± 0.56**

Glucose (mg/dL)

210 ± 11

242 ± 11

211 ± 25

Insulin (ng/mL)

1.70 ± 0.23

1.74 ± 0.18

1.79 ± 0.31

Adiponectin (ng/mL)

3.58 ± 0.11

3.51 ± 0.15

3.30 ± 0.13

  1. Each value represents as the means ± S.E.M. for six mice. †Total white adipose tissue weight represents the sum of abdominal and subcutaneous white adipose tissue weights. §Abdominal white adipose tissue weight represents the sum of epididymal, perirenal and omental white adipose tissue weights. Asterisk shows significant differences when compared to the control group by Dunnett’s test (*: P < 0.05, **: P < 0.01).