Table 1 Genotype and allele frequency distribution of LPA SNPs in CAD patients
Subjects | All patients | Patients without MACE, n = 415 | Patients with MACE, n = 102 | P | |
|---|---|---|---|---|---|
N = 517 | |||||
SNP ID | n (%) | n (%) | n (%) | ||
rs6415084 | Genotype | ||||
CC | 406 (78.5) | 367 (78.6) | 39 (78.0) | 0.250 | |
CT | 105 (20.3) | 94 (20.1) | 11 (22.0) | ||
TT | 6 (1.2) | 25 (1.3) | 0 (0.0) | ||
Allele | |||||
C | 917 (88.7) | 828 (85.2) | 89 (89.0) | 0.302 | |
T | 117 (11.3) | 144 (14.8) | 11 (11.0) | ||
rs3798220 | Genotype | ||||
CC | 433 (83.8) | 393 (84.2) | 40 (68.1) | 0.449 | |
CG | 84 (16.2) | 74 (15.8) | 10 (21.3) | ||
Allele | |||||
C | 950 (91.9) | 860 (91.1) | 74 (84.1) | 0.870 | |
G | 84 (8.1) | 74(8.9) | 14 (15.9) | ||
rs10455872 | Genotype | ||||
AA | 515 (99.6) | 465 (99.6) | 50 (100.0) | 1.000 | |
AG | 2 (0.4) | 2 (0.4) | 0 (0.0) | ||
Allele | |||||
A | 1032 (99.8) | 932 (99.8) | 100 (100.0) | 1.000 | |
G | 2 (0.2) | 2 (0.2) | 0 (0.0) |