Skip to main content
Figure 3 | Lipids in Health and Disease

Figure 3

From: Sildenafil ameliorates biomarkers of genotoxicity in an experimental model of spontaneous atherosclerosis

Figure 3

Detection of DNA damage in liver cells assessed by alkaline comet assay. (A) Typical comets showing higher DNA fragmentation in apoE-/- vehicle compared to control WT, which contrasts with apoE-/- sildenafil; (B) Bar graph showing the mean of percentage of DNA in tail; (C) Bar graph showing the mean of tail moment (in a.u.); (D) Bar graph showing the mean of the number of comets with moderate-to-high damage (more than 25% of DNA in the tail). The values are presented as means ± SEM; 6 to 8 animals per group. *p < 0.05 and **p < 0.01, ANOVA).

Back to article page