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Figure 3 | Lipids in Health and Disease

Figure 3

From: Phenotypic alterations in human saphenous vein culture induced by tumor necrosis factor-alpha and lipoproteins: a preliminary development of an initial atherosclerotic plaque model

Figure 3

Foam cell formation in HSV cultured with T + LDL. The photomicrographs of SMC foam cells in a HSV ring stimulated with T (5 ng/ml) + oxLDL (50 μg/ml) for 14 days, with immunostaining to alpha actin in cytoplasm of SMC, original magnification x40 (A), and at x1,000 (B). SMC foam cells were identified by Oil-red-O staining, original magnification x1000 (C); and transmission electron microscope, original magnification x8,000 (D) from the same experiment comparing to those in the syngeneic HSV on day 0 at the same original magnification (inlets in B, C, and D). (E) Percentages of SMC foam cells in HSV rings were compared among all groups as mentioned above. Data represent means ± SEM from 3 - 6 independent experiments. Significant differences among groups are indicated; * p- valves = 0.00, and *** p- valves = not significant.

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Lipids in Health and Disease

ISSN: 1476-511X