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Figure 3 | Lipids in Health and Disease

Figure 3

From: Phytanic acid stimulates glucose uptake in a model of skeletal muscles, the primary porcine myotubes

Figure 3

Glucose uptake and glycogen synthesis with or without PA as a function of insulin. Glucose uptake (a) was carried out on differentiated myotubes that had been incubated with (full circles) or without (open circles) 10 μM PA for 4 h, followed by different concentrations of insulin during the last 1 h. Glycogen syntheses (b) were performed on myotubes treated with (full circles) or without (open circles) 10 μM PA for 4 h, followed by 0–100 nM insulin for 2 h. Control samples lacked PA and insulin. Data are expressed as LSmean values collected from three-four wells, carried out in three separate experiments with cells isolated from a different pig each time. LSmeans with different letters (a-d) denote significantly different responses related to the insulin concentration, while * denotes LSmeans with significantly different responses with or without PA; (P < 0.05).

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