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Table 2 Glucose uptake in response to PA and PAM

From: Phytanic acid stimulates glucose uptake in a model of skeletal muscles, the primary porcine myotubes

Fatty acid concentration (μM)

Glucose uptake

 

PA

PAM

Control (0)

1.00a ± 0.045

1.00a ± 0.067

1

1.23b ± 0.105

1.09a ± .051

5

1.29b ± 0.071

 

10

1.32b ± 0.075

1.14a ± 0.061

20

1.34b ± 0.166

 

40

1.37b ± 0.076

 

50

 

0.92a ± 0.032

60

1.37b ± 0.079

 

100

 

0.75b ± 0.032

200

 

0.48c ± 0.04

400

 

0.32d ± 0.028

  1. Glucose uptake was carried out on differentiated myotubes that had been incubated with 1–60 μM PA or 1and 10 μM PAM for 4 h. PAM from 50–400 μM was administered for 24 h. Control samples lacked fatty acids. Data are expressed as LSmean values of triplicate wells, carried out in three separate experiments with cells isolated from a different pig each time. LSmeans with different letters (a-d) within each row denote significantly different responses related to fatty acid treatments; (P < 0.05).