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Table 1 Antioxidant and oxidative stress biomarkers in blood and liver of Wistar rats fed the oil supplements

From: Protective effect of the omega-3 polyunsaturated fatty acids: Eicosapentaenoic acid/Docosahexaenoic acid 1:1 ratio on cardiovascular disease risk markers in rats

Biomarkers EPA/DHA 1:1 EPA/DHA 2:1 EPA/DHA 1:2 Soybean oil Linseed oil
  Mean ± SD Mean ± SD p Mean ± SD P Mean ± SD p Mean ± SD p
Erythrocytes
SOD (U/g Hb) 2129.2 ± 586.5 1880.9 ± 341.2   1226.1 ± 517.4 a0.023 1443.8 ± 426.2   1230.6 ± 283.9 a0.017
CAT (mmol/min/g Hb) 57.4 ± 11.1 76.7 ± 28.2   61.4 ± 13.2   41.5 ± 34.6   37.2 ± 20.9  
GR (U/g Hb) 0.40 ± 0.08 0.734 ± 0.21   0.63 ± 0.35   0.93 ± 0.18   0.75 ± 0.20  
GPx (U/g Hb) 107.1 ± 15.0 116.7 ± 30.7 a0.007 67.7 ± 34.5 a0.026 101.5 ± 38.2   71.1 ± 9.6 a0.002
     b0.007     b0.001
Plasma
ORAC (μmol TE/ml plasma) 48.15 ± 16.96 23.56 ± 5.97 a0.023 26.39 ± 9.01 a0.016 30.32 ± 9.64 a0.049 24.71 ± 9.70 a0.033
LDL-ox (ng/mL) 161.53 ± 30.9 212.25 ± 57.4   239.43 ± 70.02   109.03 ± 27.34 b0.007 94.52 ± 14.08 b0.001
       c0.001   c0.001
Liver
MDA (μg MDA/ g tissue) 10.29 ± 2.82 7.57 ± 2.55   8.81 ± 3.28   8.12 ± 2.53   6.53 ± 1.24  
  1. The data are expressed as mean ± SD (standard deviation). a: difference with respect to EPA/DHA 1:1 supplementation; b: differences with respect to EPA/DHA 2:1 supplementation; c: differences with respect to EPA/DHA 1:2 supplementation.