A fish protein hydrolysate diet affected inflammation in TNFα mice. hTNFα transgenic mice were given a 15% (w/w) fish protein hydrolysate (FPH) diet for two weeks and fasted over night. The anti-inflammatory index (n = 5) was calculated from wt% of fatty acids ((C22:5n-3 + C22:6n-3 + C20:3n-6 + C20:5n-3)/C20:4n-6)*100 (a). The plasma level of INFγ (b), IL-1b (c), IL-2 (d), IL-5 (e), GM-CFS (f), and adiponectin (g) was determined (n = 4–5) . Data are given as means ± SD, and values significantly different from control are indicated (**P < 0.01).