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Table 2 Morphometric and metabolic parameters in LZR and OZR rats fed CON, FLAX, FISH, or SDA diets for 12 weeks

From: Effect of stearidonic acid-enriched soybean oil on fatty acid profile and metabolic parameters in lean and obese Zucker rats

  Lean Obese Main effects  
  CON FLAX FISH SDA CON FLAX FISH SDA Genotype Diet Interaction
Total EI ( kcal ) 7588 ± 231 7381 ± 230 7296 ± 228 7276 ± 235 9208 ± 249 9595 ± 219 9069 ± 238 8824 ± 264 P < 0.0001 P = 0.09 P = 0.30
Body weight ( g ) 497.9 ± 15.7 481.3 ± 15.6 487.8 ± 15.4 485.7 ± 15.9 635.6 ± 16.8 647.7 ± 14.9 626.7 ± 16.1 611.0 ± 17.9 P < 0.0001 P = 0.47 P = 0.43
Body fat mass (%) 15.35 ± 0.98 15.24 ± 0.97 15.53 ± 0.96 13.53 ± 0.99 47.79 ± 1.05 49.86 ± 0.93 48.23 ± 1.01 45.84 ± 1.12 P < 0.0001 P = 0.0038i P = 0.22
Body lean mass ( % ) 68.27 ± 0.85 68.58 ± 0.84 68.09 ± 0.84 69.68 ± 0.86 40.31 ± 0.91 38.87 ± 0.81 39.75 ± 0.87 41.31 ± 0.97 P < 0.0001 P = 0.050ii P = 0.61
Adj. liver weight ( % ) 2.60 ± 0.16 2.67 ± 0.16 2.88 ± 0.16 2.79 ± 0.16 3.67 ± 0.17 3.75 ± 0.15 3.49 ± 0.16 3.41 ± 0.18 P < 0.0001 P = 0.81 P = 0.17
Liver fat mass ( % ) 9.15 ± 1.36a 8.01 ± 1.35a 10.30 ± 1.34a 9.22 ± 1.39a 20.52 ± 1.45cd 21.72 ± 1.28d 15.97 ± 1.38b 18.60 ± 1.48bc P < 0.0001 P = 0.37 ΔP = 0.0053
Liver lean mass (%) 87.47 ± 1.73c 85.41 ± 1.72c 86.10 ± 1.70c 84.04 ± 1.76c 73.05 ± 1.44a 72.94 ± 1.62a 78.46 ± 1.35b 76.56 ± 1.48b P < 0.0001 P = 0.19 ΔP = 0.039
Glucose (AUC) 2580 ± 173 2364 ± 171 2618 ± 170 2540 ± 176 2740 ± 184 2544 ± 174 3055 ± 176 3074 ± 189 P = 0.017 P = 0.35 P = 0.46
Glucose to insulin ratio 17.69 ± 3.40 23.54 ± 3.32 17.37 ± 3.28 18.46 ± 3.42 1.15 ± 3.50 4.32 ± 3.31 1.21 ± 3.34 1.45 ± 3.59 P = 0.0003 P = 0.28 P = 0.77
Insulin ( pmol/L ) 0.90 ± 1.10 0.83 ± 1.07 2.32 ± 1.06 1.00 ± 1.10 5.92 ± 1.16 4.09 ± 1.07 6.19 ± 1.08 5.57 ± 1.16 P = 0.0057 P = 0.25 P = 0.94
  1. ΔDifferent letters represent significance among means as determined by Bonferroni correction (P < 0.05).
  2. Genotype Effect: Lean > Obese; Obese > Lean.
  3. Diet Effect: iCON, FLAX, FISH > SDA; iiSDA > CON, FLAX, FISH.