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Table 2 Morphometric and metabolic parameters in LZR and OZR rats fed CON, FLAX, FISH, or SDA diets for 12 weeks

From: Effect of stearidonic acid-enriched soybean oil on fatty acid profile and metabolic parameters in lean and obese Zucker rats

 

Lean

Obese

Main effects

 
 

CON

FLAX

FISH

SDA

CON

FLAX

FISH

SDA

Genotype

Diet

Interaction

Total EI ( kcal )

7588 ± 231

7381 ± 230

7296 ± 228

7276 ± 235

9208 ± 249

9595 ± 219

9069 ± 238

8824 ± 264

P < 0.0001‡

P = 0.09

P = 0.30

Body weight ( g )

497.9 ± 15.7

481.3 ± 15.6

487.8 ± 15.4

485.7 ± 15.9

635.6 ± 16.8

647.7 ± 14.9

626.7 ± 16.1

611.0 ± 17.9

P < 0.0001‡

P = 0.47

P = 0.43

Body fat mass (%)

15.35 ± 0.98

15.24 ± 0.97

15.53 ± 0.96

13.53 ± 0.99

47.79 ± 1.05

49.86 ± 0.93

48.23 ± 1.01

45.84 ± 1.12

P < 0.0001‡

P = 0.0038i

P = 0.22

Body lean mass ( % )

68.27 ± 0.85

68.58 ± 0.84

68.09 ± 0.84

69.68 ± 0.86

40.31 ± 0.91

38.87 ± 0.81

39.75 ± 0.87

41.31 ± 0.97

P < 0.0001†

P = 0.050ii

P = 0.61

Adj. liver weight ( % )

2.60 ± 0.16

2.67 ± 0.16

2.88 ± 0.16

2.79 ± 0.16

3.67 ± 0.17

3.75 ± 0.15

3.49 ± 0.16

3.41 ± 0.18

P < 0.0001‡

P = 0.81

P = 0.17

Liver fat mass ( % )

9.15 ± 1.36a

8.01 ± 1.35a

10.30 ± 1.34a

9.22 ± 1.39a

20.52 ± 1.45cd

21.72 ± 1.28d

15.97 ± 1.38b

18.60 ± 1.48bc

P < 0.0001‡

P = 0.37

ΔP = 0.0053

Liver lean mass (%)

87.47 ± 1.73c

85.41 ± 1.72c

86.10 ± 1.70c

84.04 ± 1.76c

73.05 ± 1.44a

72.94 ± 1.62a

78.46 ± 1.35b

76.56 ± 1.48b

P < 0.0001†

P = 0.19

ΔP = 0.039

Glucose (AUC)

2580 ± 173

2364 ± 171

2618 ± 170

2540 ± 176

2740 ± 184

2544 ± 174

3055 ± 176

3074 ± 189

P = 0.017

P = 0.35

P = 0.46

Glucose to insulin ratio

17.69 ± 3.40

23.54 ± 3.32

17.37 ± 3.28

18.46 ± 3.42

1.15 ± 3.50

4.32 ± 3.31

1.21 ± 3.34

1.45 ± 3.59

P = 0.0003‡

P = 0.28

P = 0.77

Insulin ( pmol/L )

0.90 ± 1.10

0.83 ± 1.07

2.32 ± 1.06

1.00 ± 1.10

5.92 ± 1.16

4.09 ± 1.07

6.19 ± 1.08

5.57 ± 1.16

P = 0.0057‡

P = 0.25

P = 0.94

  1. ΔDifferent letters represent significance among means as determined by Bonferroni correction (P < 0.05).
  2. Genotype Effect: †Lean > Obese; ‡Obese > Lean.
  3. Diet Effect: iCON, FLAX, FISH > SDA; iiSDA > CON, FLAX, FISH.