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Table 4 Hepatic fatty acid composition in LZR and OZR rats fed CON, FLAX, FISH, or SDA diets for 12 weeks

From: Effect of stearidonic acid-enriched soybean oil on fatty acid profile and metabolic parameters in lean and obese Zucker rats

Fatty acid ( % of total) Lean Obese Main effects  
  CON FLAX FISH SDA CON FLAX FISH SDA Genotype Diet Interaction
LA [18:2(n-6)] 1.19 ± 1.41 n.d. n.d. 2.07 ± 1.42 0.86 ± 1.51 0.55 ± 1.19 0.99 ± 1.42 2.08 ± 1.49 P = 0.71 P = 0.25 P = 0.84
ALA [18:3(n-3)] 0.21 ± 0.17a 3.08 ± 0.17d 0.93 ± 0.18b 3.26 ± 0.17d 0.43 ± 0.18ab 1.78 ± 0.14c 0.63 ± 0.17ab 1.88 ± 0.18c P = 0.0016 P < 0.0001i ΔP < 0.0001
SDA [18:4(n-3)] n.d. 0.018 ± 0.26 0.81 ± 0.27 1.07 ± 0.25 0.15 ± 0.27 0.14 ± 0.21 0.19 ± 0.25 0.58 ± 0.26 P = 0.51 P = 0.0011ii P = 0.17
AA [20:4(n-6)] 14.09 ± 0.83c 11.41 ± 0.85b 3.58 ± 0.89a 11.03 ± 0.83b 5.53 ± 0.89a 4.86 ± 0.70a 4.24 ± 0.83a 5.97 ± 0.88a P < 0.0001 P < 0.0001iii ΔP < 0.0001
EPA [20:5(n-3)] n.d. 0.50 ± 0.61a 6.20 ± 0.63c 4.94 ± 0.60c 0.63 ± 0.63a 0.79 ± 0.50a 2.37 ± 0.60b 2.67 ± 0.63b P = 0.12 P < 0.0001ii ΔP < 0.0001
DPA [22:5(n-3)] 0.12 ± 0.22a 1.33 ± 0.23bc 3.36 ± 0.24d 3.94 ± 0.22e 0.42 ± 0.24ab 0.77 ± 0.19b 1.70 ± 0.22c 1.88 ± 0.24c P = 0.0006 P < 0.0001iv ΔP < 0.0001
DHA [22:6(n-3)] 2.26 ± 0.39ab 4.49 ± 0.40cd 10.11 ± 0.42e 3.28 ± 0.39bf 1.87 ± 0.42a 2.43 ± 0.33ab 5.63 ± 0.39d 3.36 ± 0.41bc P = 0.0007 P < 0.0001v ΔP < 0.0001
∑SFA 36.48 ± 1.55c 36.12 ± 1.59c 27.83 ± 1.66a 32.41 ± 1.56b 38.85 ± 1.66d 41.14 ± 1.30d 39.88 ± 1.56d 39.43 ± 1.64d P = 0.0010 P = 0.0055vi ΔP = 0.0079
∑MUFA 41.99 ± 1.90 38.02 ± 1.85 33.93 ± 1.94 31.47 ± 1.82 46.57 ± 1.92 44.30 ± 1.51 39.91 ± 1.80 38.08 ± 1.90 P = 0.032 P = 0.0084vi P = 0.90
∑n3PUFA 1.92 ± 1.26a 9.38 ± 1.29b 21.82 ± 1.35d 16.88 ± 1.27c 3.65 ± 1.35a 6.02 ± 1.06e 10.76 ± 1.27b 10.94 ± 1.33b P = 0.048 P < 0.0001iv ΔP = 0.0057
∑n6PUFA 15.28 ± 1.70a 10.6 ± 1.74bc 3.04 ± 1.82d 13.1 ± 1.71ab 6.39 ± 1.82de 5.41 ± 1.43de 5.23 ± 1.71de 8.05 ± 1.80ce P = 0.0040 P < 0.0001iii ΔP < 0.0001
  1. ΔDifferent letters represent significance among means as determined by Bonferroni correction (P < 0.05).
  2. Genotype Effect: Lean > Obese; Obese > Lean.
  3. Diet Effect: iSDA, FLAX > FISH, CON; iiSDA, FISH > FLAX, CON; iiiCON > SDA, FLAX > FISH; ivFISH > SDA > FLAX > CON; vFISH > SDA, FLAX > CON; viCON, FLAX > FISH, SDA.
  4. n.d.- not detectable.