Table 4 Hepatic fatty acid composition in LZR and OZR rats fed CON, FLAX, FISH, or SDA diets for 12 weeks

1.19 ± 1.41

n.d.

n.d.

2.07 ± 1.42

0.86 ± 1.51

0.55 ± 1.19

0.99 ± 1.42

2.08 ± 1.49

P = 0.71

P = 0.25

P = 0.84

0.21 ± 0.17^a

3.08 ± 0.17^d

0.93 ± 0.18^b

3.26 ± 0.17^d

0.43 ± 0.18^ab

1.78 ± 0.14^c

0.63 ± 0.17^ab

1.88 ± 0.18^c

P = 0.0016^†

P < 0.0001ⁱ

^ΔP < 0.0001

n.d.

0.018 ± 0.26

0.81 ± 0.27

1.07 ± 0.25

0.15 ± 0.27

0.14 ± 0.21

0.19 ± 0.25

0.58 ± 0.26

P = 0.51

P = 0.0011ⁱⁱ

P = 0.17

14.09 ± 0.83^c

11.41 ± 0.85^b

3.58 ± 0.89^a

11.03 ± 0.83^b

5.53 ± 0.89^a

4.86 ± 0.70^a

4.24 ± 0.83^a

5.97 ± 0.88^a

P < 0.0001^†

P < 0.0001ⁱⁱⁱ

^ΔP < 0.0001

n.d.

0.50 ± 0.61^a

6.20 ± 0.63^c

4.94 ± 0.60^c

0.63 ± 0.63^a

0.79 ± 0.50^a

2.37 ± 0.60^b

2.67 ± 0.63^b

P = 0.12

P < 0.0001ⁱⁱ

^ΔP < 0.0001

0.12 ± 0.22^a

1.33 ± 0.23^bc

3.36 ± 0.24^d

3.94 ± 0.22^e

0.42 ± 0.24^ab

0.77 ± 0.19^b

1.70 ± 0.22^c

1.88 ± 0.24^c

P = 0.0006^†

P < 0.0001^iv

^ΔP < 0.0001

2.26 ± 0.39^ab

4.49 ± 0.40^cd

10.11 ± 0.42^e

3.28 ± 0.39^bf

1.87 ± 0.42^a

2.43 ± 0.33^ab

5.63 ± 0.39^d

3.36 ± 0.41^bc

P = 0.0007^†

P < 0.0001^v

^ΔP < 0.0001

36.48 ± 1.55^c

36.12 ± 1.59^c

27.83 ± 1.66^a

32.41 ± 1.56^b

38.85 ± 1.66^d

41.14 ± 1.30^d

39.88 ± 1.56^d

39.43 ± 1.64^d

P = 0.0010^‡

P = 0.0055^vi

^ΔP = 0.0079

41.99 ± 1.90

38.02 ± 1.85

33.93 ± 1.94

31.47 ± 1.82

46.57 ± 1.92

44.30 ± 1.51

39.91 ± 1.80

38.08 ± 1.90

P = 0.032^†

P = 0.0084^vi

P = 0.90

1.92 ± 1.26^a

9.38 ± 1.29^b

21.82 ± 1.35^d

16.88 ± 1.27^c

3.65 ± 1.35^a

6.02 ± 1.06^e

10.76 ± 1.27^b

10.94 ± 1.33^b

P = 0.048^†

P < 0.0001^iv

^ΔP = 0.0057

15.28 ± 1.70^a

10.6 ± 1.74^bc

3.04 ± 1.82^d

13.1 ± 1.71^ab

6.39 ± 1.82^de

5.41 ± 1.43^de

5.23 ± 1.71^de

8.05 ± 1.80^ce

P = 0.0040^†

P < 0.0001ⁱⁱⁱ

^ΔP < 0.0001