Fatty acid ( % of total) | Lean | Obese | Main effect | Â | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
 | CON | FLAX | FISH | SDA | CON | FLAX | FISH | SDA | Genotype | Diet | Interaction |
LA [18:2(n-6)] | 0.005 ± 0.002 | 0.009 ± 0.002 | 0.005 ± 0.002 | 0.009 ± 0.002 | 0.007 ± 0.002 | 0.007 ± 0.001 | 0.010 ± 0.002 | 0.012 ± 0.002 | P = 0.13 | P = 0.48 | P = 0.35 |
ALA [18:3(n-3)] | 1.31 ± 0.030 | 1.36 ± 0.030 | 1.28 ± 0.028 | 1.23 ± 0.030 | 1.19 ± 0.030 | 1.20 ± 0.024 | 1.16 ± 0.030 | 1.05 ± 0.030 | P < 0.0001†| P < 0.0001i | P = 0.58 |
SDA [18:4(n-3)] | 0.16 ± 0.027 | 0.14 ± 0.027 | 0.18 ± 0.026 | 0.18 ± 0.027 | 0.08 ± 0.028 | 0.10 ± 0.022 | 0.13 ± 0.027 | 0.12 ± 0.027 | P = 0.078 | P = 0.30 | P = 0.83 |
AA [20:4(n-6)] | 11.02 ± 0.20de | 10.69 ± 0.20cd | 9.80 ± 0.19b | 10.65 ± 0.20cd | 11.19 ± 0.21e | 10.27 ± 0.16bc | 8.87 ± 0.20a | 10.48 ± 0.20cd | P = 0.16 | P < 0.0001ii | ΔP = 0.021 |
EPA [20:5(n-3)] | 0.023 ± 0.01a | 0.028 ± 0.01a | 0.13 ± 0.01c | 0.079 ± 0.01b | 0.018 ± 0.01a | 0.066 ± 0.0b | 0.24 ± 0.01e | 0.20 ± 0.01d | P < 0.0001‡ | P < 0.0001iii | ΔP < 0.0001 |
DPA [22:5(n-3)] | 0.13 ± 0.018a | 0.28 ± 0.018b | 0.46 ± 0.017c | 0.66 ± 0.018e | 0.13 ± 0.018a | 0.33 ± 0.014b | 0.56 ± 0.018d | 0.81 ± 0.018f | P = 0.0009‡ | P < 0.0001iv | ΔP < 0.0001 |
DHA [22:6(n-3)] | 12.80 ± 0.22 | 13.53 ± 0.21 | 14.38 ± 0.21 | 13.53 ± 0.22 | 13.52 ± 0.22 | 13.61 ± 0.17 | 15.06 ± 0.22 | 13.90 ± 0.22 | P = 0.077‡ | P < 0.0001v | P = 0.26 |
∑SFA | 36.00 ± 0.27 | 35.78 ± 0.26 | 35.74 ± 0.25 | 35.73 ± 0.26 | 36.35 ± 0.27 | 36.06 ± 0.21 | 35.77 ± 0.26 | 36.83 ± 0.27 | P = 0.16 | P = 0.074vi | P = 0.091 |
∑MUFA | 19.90 ± 0.16 | 20.44 ± 0.15 | 20.84 ± 0.15 | 20.1 ± 0.15 | 19.61 ± 0.16 | 20.08 ± 0.12 | 20.03 ± 0.15 | 19.82 ± 0.16 | P = 0.021†| P < 0.0001vii | P = 0.14 |
∑n3PUFA | 14.62 ± 0.21 | 15.53 ± 0.20 | 16.61 ± 0.19 | 15.85 ± 0.20 | 15.08 ± 0.21 | 15.46 ± 0.16 | 17.23 ± 0.20 | 16.29 ± 0.21 | P = 0.14 | P < 0.0001iii | P = 0.21 |
∑n6PUFA | 11.02 ± 0.20bd | 10.70 ± 0.20b | 9.80 ± 0.19b | 10.65 ± 0.20bc | 11.20 ± 0.21d | 10.28 ± 0.16c | 8.88 ± 0.20a | 10.49 ± 0.20b | P = 0.17 | P < 0.0001ii | ΔP = 0.023 |