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Table 2 Fractional clearance rates and kinetic parameters of LDE radioactive lipid labels in the Type 1 Diabetes Mellitus (T1DM) and control groups

From: Lipoprotein metabolism in patients with type 1 diabetes under intensive insulin treatment

 

T1DM group (n=15)

Control group (n=16)

P value

FCR 14C-CE

0.059 ± 0.022

0.039 ± 0.022

0.019

  k1.0 14C-CE

0.352 ± 0.278

0.502 ± 0.567

0.97

  k2.0 14C-CE

0.049 ± 0.024

0.026 ± 0.017

0.006

  k1,2 14C-CE

1.939 ± 1.464

1.436 ± 1.425

0.35

FCR 3H-FC

0.025 ± 0.024

0.028 ± 0.024

0.78

  k1,0 3H-FC

0.911 ± 0.731

0.866 ± 0.651

0.86

  k2,0 3H-FC

0.016 ± 0.021

0.011 ± 0.010

0.98

  k1,2 3H-FC

0.999 ± 0.972

0.677 ± 0.815

0.19

  1. Data are means ± SD. FCR 14C-CE, fractional clearance rate of 14C-cholesteryl ester. FCR 3H-CL, fractional clearance rate of 3H-free cholesterol. k1,0, constant that represents removal of lipid to the extravascular space. k1,2, constant that represents injected lipid which was converted into intravascular compartment. k2,0, constant that represents materials of intravascular compartment which is transferred to the extravascular space.
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Lipids in Health and Disease

ISSN: 1476-511X