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Table 2 Demographic and clinical characteristics of study participants

From: Association of COL4A1 genetic polymorphisms with coronary artery disease in Uygur population in Xinjiang, China

  Total Men Women
  CAD Control P value CAD Control P value CAD Control P value
Number(n) 471 624   327 400   144 224  
Age, mean (SD) 56.07 (8.50) 55.95 (8.35) 0.825 55.30 (8.54) 55.77 (8.46) 0.46 57.81 (8.12) 56.28 (8.17) 0.082
EH, n (%) 247 (52.4) 199 (31.9) < 0.001 159 (48.6) 129 (32.3) < 0.001 88 (61.6) 70 (31.3) < 0.001
Diabetes, n (%) 99 (21.0) 20 (3.2) < 0.001 65 (19.9) 20 (5.0) < 0.001 34 (23.6) 0 < 0.001
Smoking, n (%) 178 (37.8) 178 (28.50) 0.001 178 (54.4) 177 (43.3) 0.007 0 1 (4%) 1
Drinking, n (%) 70 (14.9) 80 (12.8) 0.375 70 (21.4) 79 (19.8) 0.644 0 1 (4%) 1
BMI, mean (SD) 27.34 (3.69) 25.24 (4.32) < 0.001 27.47 (3.66) 25.23 (3.94) < 0.001 27.06 (3.75) 25.26 (4.93) < 0.001
SBP, mean (SD) 141.13 (29.32) 129.96 (19.57) < 0.001 138.80 (29.31) 130.41 (19.56) < 0.001 146.43 (28.74) 129.16 (19.61) < 0.001
DBP, mean (SD) 87.74 (19.27) 80.03 (13.93) < 0.001 86.74 (19.38) 80.57 (14.14) < 0.001 89.59 (18.92) 79.08 (13.52) < 0.001
Glu, mean (SD) 6.10 (2.41) 4.83 (1.35) < 0.001 6.05 (2.38) 4.87 (1.58) < 0.001 6.22 (2.50) 4.77 (0.79) < 0.001
TG, mean (SD) 1.10 (1.16) 1.58 (1.08) < 0.001 1.96 (1.16) 1.57 (1.12) < 0.001 2.08 (1.15) 1.59 (1.02) < 0.001
TC, mean (SD) 4.20 (1.10) 4.38 (1.06) 0.008 4.08 (0.98) 4.28 (1.01) 0.009 4.47 (1.28) 4.55 (1.11) 0.548
HDL, mean (SD) 0.94 (0.55) 1.26 (0.42) < 0.001 0.91 (0.52) 1.28 (0.43) < 0.001 1.01 (0.59) 1.25 (0.41) < 0.001
LDL, mean (SD) 2.60 (1.00) 2.88 (0.97) < 0.001 2.55 (0.99) 2.85 (0.95) < 0.001 2.73 (1.03) 2.91 (1.01) 0.086
UA, mean (SD) 311.92 (86.07) 261.58 (73.79) < 0.001 324.71 (81.03) 279.23 (72.68) < 0.001 283.00 (90.50) 230.08 (64.84) < 0.001
Cr, mean (SD) 78.77 (33.05) 78.34 (33.68) 0.833 83.69 (33.87) 85.98 (36.67) 0.385 67.58 (28.17) 64.68 (21.68) 0.226
BUN, mean (SD) 5.54 (2.29) 5.37 (1.92) 0.182 5.54 (2.37) 5.52 (2.07) 0.94 5.54 (2.11) 5.09 (1.59) 0.02
  1. Continuous variables are expressed as mean ± SD. Categorical variables are expressed as percentages.
  2. BMI, body mass index; BUN, blood urea nitrogen; Cr, creatinine; DBP, diastolic blood pressure; DM, diabetes mellitus; Glu, glucose; TG, triglyceride; TC, total cholesterol; HDL, high density lipoprotein; LDL, low density lipoprotein; EH, essential hypertension; SBP, systolic blood pressure; UA, uric acid;
  3. The P value of the continuous variables was calculated by the Independent t-test.
  4. The P value of the categorical variables was calculated by Fisher’s exact test.