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Table 2 Association between the APOE epsilon polymorphism and anthropometric, biochemical and clinical parameters in the ISOR study

From: Impact of APOE gene polymorphisms on the lipid profile in an Algerian population

  ϵ2ϵ2+ϵ2ϵ3 ϵ3ϵ3 ϵ3ϵ4+ϵ4ϵ4 p a p b
n 67 522 137   
Weight (kg) 74.6 ± 17.9 71.0 ± 14.2 70.7 ± 13.6 0.05 0.6
Waist (cm) 89.4 ± 13.3 87.6 ± 12.5 87.4 ± 11.6 0.33 0.81
Hip (cm) 103.0 ± 10.6 101.9 ± 9.7 101.0 ± 9.3 0.16 0.6
BMI (kg/m2) 27.3 ± 6.2 26.1 ± 5.1 25.5 ± 4.5 0.02 0.42
Waist-to-hip ratio 0.87 ± 0.08 0.86 ± 0.09 0.87 ± 0.08 0.93 0.71
Fasting glucose (mmol/L)* 4.98 ± 1.28 5.04 ± 1.30 5.20 ± 1.53 0.23 0.25
Fasting insulin (μIU/mL)* 9.18 ± 6.65 7.95 ± 5.48 8.65 ± 8.31 0.76 0.35
Triglycerides (mmol/L) 1.34 ± 0.78 1.09 ± 0.44 1.24 ± 0.48 0.10 0.0002
Total cholesterol (mmol/L) 4.25 ± 0.95 4.41 ± 0.86 4.63 ± 1.11 0.10 0.009
HDL-cholesterol (mmol/L) 1.27 ± 0.34 1.26 ± 0.30 1.22 ± 0.32 0.40 0.06
LDL-cholesterol (mmol/L) 2.47 ± 0.85 2.64 ± 0.82 2.88 ± 1.05 0.06 0.003
LDL-cholesterol/HDL-cholesterol ratio 2.14 ± 1.07 2.25 ± 1.00 2.55 ± 1.23 0.18 0.001
SBP (mmHg)†† 122.6 ± 16.3 120.6 ± 14.8 122.7 ± 17.8 0.95 0.13
DBP (mmHg)†† 75.5 ± 8.8 76.6 ± 9.8 76.3 ± 11.1 0.83 0.38
  1. Data are expressed as the mean ± SD. SBP: systolic blood pressure; DBP: diastolic blood pressure.
  2. p values were adjusted for age, gender, smoking status and physical activity for anthropometric variables.
  3. p values were adjusted for age, gender, BMI, smoking status and physical activity for biological and biochemical variables.
  4. pa: p values obtained when comparing ϵ2ϵ2+ϵ2ϵ3 subjects with ϵ3ϵ3 subjects.
  5. pb: p values obtained when comparing ϵ3ϵ4+ϵ4ϵ4 subjects with ϵ3ϵ3 subjects.
  6. *subjects treated for diabetes were excluded (n=54).
  7. subjects treated with lipid-lowering drugs were excluded (n=36).
  8. ††subjects treated for hypertension were excluded (n=89).