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Table 4 Effect of the APOE haplotypes on plasma LDL-cholesterol levels in the ISOR study

From: Impact of APOE gene polymorphisms on the lipid profile in an Algerian population

Haplotypes    
rs429358/rs7412/rs4420638 ϵ/rs4420638 Frequency Haplotype effect [95% CI] (mmol/L) p
TCA ϵ3A 0.784 reference -
TCG ϵ3G 0.061 0.02 [-0.17 ─ 0.21] 0.74
CCA ϵ4A 0.054 0.35 [0.18 ─ 0.51] 0.0001
CCG ϵ4G 0.051 -0.05 [-0.27 ─ 0.17] 0.81
TTA ϵ2A 0.050 -0.20 [-0.41 ─ -0.01] 0.05
  1. Polymorphisms are ordered according to their position in the genomic sequence.
  2. Values are the difference in means [95% CI] when compared with the ϵ3A reference haplotype (mean [95% CI]=1.33 [1.29 ─ 1.37] mmol/L) using Thesias software.