Skip to main content

Table 4 Effect of the APOE haplotypes on plasma LDL-cholesterol levels in the ISOR study

From: Impact of APOE gene polymorphisms on the lipid profile in an Algerian population

Haplotypes

   

rs429358/rs7412/rs4420638

ϵ/rs4420638

Frequency

Haplotype effect [95% CI] (mmol/L)

p

TCA

ϵ3A

0.784

reference

-

TCG

ϵ3G

0.061

0.02 [-0.17 ─ 0.21]

0.74

CCA

ϵ4A

0.054

0.35 [0.18 ─ 0.51]

0.0001

CCG

ϵ4G

0.051

-0.05 [-0.27 ─ 0.17]

0.81

TTA

ϵ2A

0.050

-0.20 [-0.41 ─ -0.01]

0.05

  1. Polymorphisms are ordered according to their position in the genomic sequence.
  2. Values are the difference in means [95% CI] when compared with the ϵ3A reference haplotype (mean [95% CI]=1.33 [1.29 ─ 1.37] mmol/L) using Thesias software.
Back to article page

Lipids in Health and Disease

ISSN: 1476-511X