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Table 3 Fatty acid content and fold increase in LA, GLA, AA, ALA, EPA and DHA in RWPE-1 and PC-3 cells supplemented with these fatty acids as compared to control

From: Effect of n-3 and n-6 unsaturated fatty acids on prostate cancer (PC-3) and prostate epithelial (RWPE-1) cells in vitro

Fatty acid supplemented RWPE-1 cells Fold increase compared to control PC-3 cells Fold increase compared to control
Control - LA 0.38 ± 0.09 - 0.14 ± 0.01 -
LA 50 μM 1.59 ± 0.13 4.18 0.80 ± 0.10 5.71
LA 150 μM 0.52 ± 0.18 1.37 1.92 ± 0.38 13.71
Control - GLA 0.76 ± 0.13 - 0.88 ± 0.03 -
GLA 25 μM 1.44 ± 0.09 1.89 0.97 ± 0.08 1.10
GLA 50 μM 1.01 ± 0.13 1.33 1.08 ± 0.28 1.23
GLA 75 μM 12.34 ± 0.55 17.63 0.76 ± 0.01 < 1.0
Control- AA 0.92 ± 0.14 - 1.22 ± 0.03 -
AA 50 μM 7.01 ± 0.74 7.62 14.28 ± 0.44 11.70
AA 100 μM 10.28 ± 0.43 11.17 22.20 ± 0.63 18.20
Control- ALA 0.47 ± 0.09 - 0.12 ±0.01 -
ALA 50 μM 0.62 ± 0.13 1.32 0.51 ± 0.13 4.25
ALA 150 μM 0.86 ± 0.10 1.83 2.13 ± 0.18 17.75
Control- EPA 0.86 ± 0.13 - N.D. -
EPA 50 μM 1.14 ± 0.25 1.33 2.78 ± 0.03 >2.78
EPA 100 μM 4.42 ± 0.43 3.88 5.64 ± 1.80 >5.64
Control-DHA 2.58 ± 0.49 - 0.71 ± 0.03 -
DHA 50 μM 14.95 ± 0.63 5.79 11.17 ± 1.08 15.73
DHA 100 μM 15.35 ± 0.08 5.95 19.08 ±0.06 26.87