Table 4 Changes seen in the survival, FR generated, and LXA ₄ , TNF-α and IL-6 secreted by RWPE-1 cells when supplemented with different doses of fatty acids for 48 hours

Control

100 ± 3.49

100 ± 5.40

100 ± 0.43

100 ± 0.74

100 ± 6.43

LA 50 μM

94.74 ± 7.01*

104.61 ± 10.00*

48.75 ± 10.46***

86.96 ± 11.94**

165.71 ± 8.60***

LA 150 μM

73.68 ± 3.58**

84.00 ± 7.38**

67.96 ± 4.53**

82.12 ± 11.94**

114.28 ± 10.77**

GLA 25 μM

98.39 ± 2.94*

50.66 ± 4.80***

49.91 ± 0.70***

18.70 ± 0.42***

57.03 ± 7.18***

GLA 50 μM

108.64 ± 7.30*

64.14 ± 5.10***

71.43 ± 0.79**

31.32 ± 0.51***

53.91 ± 7.47***

GLA 75 μM

85.25 ± 4.95**

78.71 ± 2.77**

80.65 ± 2.17**

42.92 ± 1.17***

89.01 ± 0.97**

AA 50 μM

106.46 ± 0.69*

71.89 ± 2.17**

60.18 ± 0.79***

99.42 ± 0.30

66.16 ± 0.94**

AA 100 μM

41.92 ± 3.93***

69.03 ± 5.77**

179.05 ± 1.95***

99.78 ± 0.23

64.73 ± 1.83**

ALA 50 μM

90.91 ± 7.35*

80.00 ± 7.34**

37.04 ± 6.00***

114.28 ± 7.49*

178.57 ± 2.85***

ALA150μM

59.09 ± 5.44**

100.23 ± 8.08

70.37 ± 6.00**

130.95 ± 6.43**

149.28 ± 5.77**

EPA 50 μM

108.2 ± 7.74*

60.60 ± 6.50***

67.00 ± 1.15**

97.30 ± 0.57

47.69 ± 3.03***

EPA 100 μM

82.61 ± 7.85**

39.47 ± 4.32***

41.69 ± 0.64***

102.22 ± 0.93

35.47 ± 6.16***

DHA 50 μM

96.47 ± 9.31*

75.69 ± 5.70**

46.42 ± 1.06***

99.60 ± 0.44

44.74 ± 3.31***

DHA100μM

85.71 ± 3.97**

74.74 ± 6.44**

51.95 ± 1.69***

111.70 ± 2.09*

54.73 ± 5.25***