Skip to main content

Table 2 Genotype and allele frequencies of apolipoprotein A1 -75 G/A polymorphism among patients with or without ALI after CPB surgery and controls

From: Association of apolipoprotein A1 -75 G/A polymorphism with susceptibility to the development of acute lung injury after cardiopulmonary bypass surgery

 

ALI (n = 300)

Without ALI (n = 300)

Healthy controls (n = 300)

ALI vs without ALI

ALI vs healthy controls

Without ALI vs healthy controls

    

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

Genotype

GG

132(44.0)

144(48.0)

138(46.0)

1.00(Reference)

 

1.00(Reference)

 

1.00(Reference)

 

GA

120(40.0)

126(42.0)

129(43.0)

1.04(0.74,1.47)

0.83

0.97(0.69,1.37)

0.87

0.94(0.67,1.31)

0.70

AA

48(16.0)

30(10.0)

33(11.0)

1.75(1.04,2.92)

0.03

1.52(0.92,2.52)

0.10

0.87(0.50,1.51)

0.62

Allele

G

384(64.0)

414(69.0)

405(67.5)

1.00(Reference)

 

1.00(Reference)

 

1.00(Reference)

 

A

216(36.0)

186(31.0)

195(32.5)

1.25(0.99,1.59)

0.07

1.17(0.92,1.48)

0.20

0.93(0.73,1.19)

0.58

  1. ALI, Acute lung injury; CPB, Cardiopulmonary bypass; vs, versus; OR, Odds ratio; CI, Confidence interval.