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Figure 1 | Lipids in Health and Disease

Figure 1

From: Reduced beta2-glycoprotein I protects macrophages from ox-LDL-induced foam cell formation and cell apoptosis

Figure 1

Typical pictures of macrophages (Oil red O staining, 320×). RAW264.7 macrophages were seeded onto 96-well microtitre plates at a density of 2 × 106 cells per well, cultured for 12 h and then serum-starved for another 24 h. Cells were incubated for another 24 h in DMEM, which was supplemented with ox-LDL alone or along with beta2-GPI or reduced beta2-GPI. Oil red O staining was performed, and macrophages were observed using an inverted microscope. Ox-LDL increased the formation of red lipid droplets in macrophages and beta2-GPI or reduced beta2-GPI decreased the formation lipid droplets, while the latter showed a stronger action than the former.

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Lipids in Health and Disease

ISSN: 1476-511X