Enhanced increase of omega-3 index in healthy individuals with response to 4-week n-3 fatty acid supplementation from krill oil versus fish oil

Vanu R Ramprasath; Inbal Eyal; Sigalit Zchut; Peter JH Jones

doi:10.1186/1476-511X-12-178

Lipids in Health and Disease

Table 2 Plasma composition of fatty acids and their changes with different interventions

From: Enhanced increase of omega-3 index in healthy individuals with response to 4-week n-3 fatty acid supplementation from krill oil versus fish oil

Parameter	Treatment	Baseline		End-Point		Change
Parameter	Treatment	Mean ± STD	P. value¹	Mean ± STD	P. value¹	Mean ± STD	P. value¹
EPA	Krill oil	0.80 ± 0.31	0.5134	1.97 ± 0.58^*#	<0.0001	1.17 ± 0.52^*#	<0.0001
	Fish oil	0.82 ± 0.36		1.54 ± 0.69^*		0.71 ± 0.46^*
	Corn oil	0.86 ± 0.36		0.79 ± 0.43		-0.06 ± 0.36
DPA	Krill oil	0.61 ± 0.31	0.9087	0.79 ± 0.27^*	0.0048	0.15 ± 0.23^*	0.0076
	Fish oil	0.64 ± 0.24		0.68 ± 0.28		0.04 ± 0.18^*
	Corn oil	0.64 ± 0.25		0.61 ± 0.16		-0.03 ± 0.19
DHA	Krill oil	2.90 ± 0.58	0.5134	3.86 ± 0.89^*	<0.0001	0.96 ± 0.69^*	<0.0001
	Fish oil	2.88 ± 0.59		3.72 ± 0.66^*		0.84 ± 0.55^*
	Corn oil	3.03 ± 0.66		2.80 ± 0.60		-0.24 ± 0.69
Total n-3 PUFA	Krill oil	4.97 ± 0.69	0.8465	7.20 ± 1.35^*#	<0.0001	2.23 ± 1.13^*#	<0.0001
	Fish oil	4.96 ± 0.59		6.51 ± 0.97^*		1.55 ± 0.83^*
	Corn oil	5.13 ± 0.95		4.79 ± 0.63		-0.34 ± 0.86
EPA + DHA	Krill oil	3.70 ± 0.63	0.7470	5.83 ± 1.31^*#	<0.0001	2.13 ± 1.02^*#	<0.0001
	Fish oil	3.70 ± 0.65		5.26 ± 0.95^*		1.55 ± 0.73^*
	Corn oil	3.89 ± 0.85		3.59 ± 0.59		-0.30 ± 0.76
n-6:n-3 ratio	Krill oil	7.06 ± 1.18	0.5818	4.88 ± 1.37^*#	<0.0001	-2.17 ± 1.05^*#	<0.0001
	Fish oil	7.21 ± 0.93		5.32 ± 0.99^*		-1.89 ± 0.91^*
	Corn oil	7.12 ± 1.4		7.57 ± 1.06		0.44 ± 0.95
Total SFA	Krill oil	43.46 ± 1.85	0.3247	43.03 ± 1.63	0.0226	-0.43 ± 1.93	0.0787
	Fish oil	42.92 ± 1.32		43.65 ± 1.06^*		0.73 ± 1.44
	Corn oil	42.13 ± 4.74		42.53 ± 2.13		0.40 ± 5.04
Total MUFA	Krill oil	17.23 ± 2.93	0.8825	16.29 ± 2.42^*	0.0226	-0.94 ± 2.86	0.8465
	Fish oil	16.84 ± 2.47		16.06 ± 1.74^*		-0.78 ± 2.51
	Corn oil	17.25 ± 3.06		16.97 ± 2.21		-0.29 ± 3.11
Total PUFA	Krill oil	39.31 ± 2.39	0.2748	40.68 ± 2.06	0.8825	1.36 ± 2.58	0.9592
	Fish oil	40.24 ± 1.98		40.28 ± 1.73		0.05 ± 2.16
	Corn oil	40.62 ± 3.92		40.51 ± 2.22		-0.11 ± 4.69
Total n-6 PUFA	Krill oil	34.35 ± 2.41	0.6873	33.48 ± 2.26^*	0.0007	-0.87 ± 2.08	0.0226
	Fish oil	35.28 ± 1.87		33.77 ± 1.75^*		-1.51 ± 2.07^*
	Corn oil	35.49 ± 3.62		35.72 ± 2.14		0.22 ± 4.09

Values are expressed as percentage of total fatty acids except the n-6:n-3 ratio (n = 24). ¹Friedman Test was used to test if there is a significant difference between treatment groups regarding the results in baseline, end-point and change. ^* and ^# indicate significant difference compared with corn and fish oil treatments respectively.

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