Figure 3From: The combination of L-4F and simvastatin stimulate cholesterol efflux and related proteins expressions to reduce atherosclerotic lesions in apoE knockout miceFold change in mRNA levels of ABCA1, SR-BI and ABCG1 in macrophage by RT- PCR. Simvastatin and L-4F could not change the expression of SR-BI in macrophages. L-4F increased the mRNA expressions ABCA1 and ABCG1, and simvastatin improved the expression of ABCA1. 1P < 0.05, 2P < 0.001, vs. AS group; aP < 0.05, bP < 0.001, vs. Simva group;*P < 0.05, **P < 0.001, vs. L-4F group.Back to article page