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Table 1 Serum TC, LDL-C, HDL-C, TG and Apo A-I levels (n = 6)

From: The combination of L-4F and simvastatin stimulate cholesterol efflux and related proteins expressions to reduce atherosclerotic lesions in apoE knockout mice

 

TC/(mmol/L)

TG/(mmol/L)

LDL-C/(mmol/L)

HDL-C/(mmol/L)

Apo A-I/(mg/ml)

W-T group

3.17 ± 0.532

0.91 ± 0.322

0.55 ± 0.102

2.27 ± 0.322

0.95 ± 0.142

AS group

22.42 ± 1.99

2.68 ± 0.28

12.45 ± 1.29

1.60 ± 0.22

0.73 ± 0.09

Simva group

14.89 ± 2.062

2.34 ± 0.171

7.59 ± 1.252

2.03 ± 0.401

0.86 ± 0.10

L-4F group

20.83 ± 2.11

2.58 ± 0.27

11.75 ± 0.92

1.73 ± 0.23

0.89 ± 0.091

Simva + L-4F

13.60 ± 2.502

2.25 ± 0.292

7.20 ± 0.682

1.99 ± 0.202

1.06 ± 0.162*

  1. 1P < 0.05, 2P < 0.001, vs. AS group; aP < 0.05, bP < 0.001, vs. Simva group.
  2. *P < 0.05, **P < 0.001, vs. L-4F group.
  3. TC (total cholesterol), TG (Triglycerides), LDL-C (low density lipoprotein cholesterol), HDL-C (high density lipoprotein cholesterol).
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Lipids in Health and Disease

ISSN: 1476-511X