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Table 2 mRNA expressions of ABCA1, SR-BI, ABCG1, LXRα and PPARγ in liver

From: The combination of L-4F and simvastatin stimulate cholesterol efflux and related proteins expressions to reduce atherosclerotic lesions in apoE knockout mice

 

ABCA1

SR-BI

ABCG1

LXRα

PPARγ

W-T group

12

12

12

12

12

AS group

0.52 ± 0.08

0.64 ± 0.06

0.75 ± 0.12

0.40 ± 0.07

0.50 ± 0.08

Simva group

0.98 ± 0.14 2

0.69 ± 0.11

1.23 ± 0.192

0.71 ± 0.072

0.96 ± 0.072

L-4F group

1.38 ± 0.12 2b

1.01 ± 0.142b

1.46 ± 0.162b

1.08 ± 0.102b

1.19 ± 0.202b

Simva + L-4F

1.51 ± 0.13 2b

1.96 ± 0.492**

1.73 ± 0.242b**

1.31 ± 0.202b**

1.52 ± 0.102b**

  1. 1P < 0.05, 2P < 0.001, vs. AS group; aP < 0.05, bP < 0.001, vs. Simva group.
  2. *P < 0.05, **P < 0.001, vs. L-4F group.
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Lipids in Health and Disease

ISSN: 1476-511X