Skip to main content

Table 1 Fasting serum lipids concentrations of the Lithuanian population (reference group) according to SCARB1 genotypes (Mean (Standard Deviation)) by gender and age

From: SCARB1 single nucleotide polymorphism (rs5888) is associated with serum lipid profile and myocardial infarction in an age- and gender-dependent manner

Characteristics

SCARB1 genotypes

Men

Women

  

25-44 years

45-64 years

65-74 years

All

25-44 years

45-64 years

65-74 years

All

  

N = 168

N = 590

N = 144

N = 902

N = 260

N = 652

N = 162

N = 1074

TChol, mmol/l

CC

5.27 (1.00)

5.52 (1.15)

5.66 (0.98)

5.49 (1.05)

4.85 (0.89)

5.85 (1.07)

6.02 (1.04)

5.63 (0.98)

 

CT

5.20 (1.02)

5.58 (1.01)

5.43 (0.98)

5.49 (1.05)

4.89 (0.88)

5.81 (1.08)

6.20 (1.01)

5.65 (1.14)

 

TT

5.5 (1.01)

5.76 (1.09)

5.75 (0.99)

5.70* (1.12)

4.75 (0.83)

5.96 (1.08)

6.41 (1.08)

5.64 (1.05)

 

Total

5.27 (1.04)

5.59 (0.97)

5.57 (0.96)

5.53 (0.90)

4.86 (0.81)

5.82 (1.02)

6.19 (1.02)

5.64 (0.98)

LDL-Chol, mmol/l

CC

3.32 (0.92)

3.48 (1.00)

3.65 (0.92)

3.48 (1.05)

2.92 (0.79)

3.68 (1.07)

3.79 (0.96)

3.51 (0.98)

 

CT

3.37 (0.93)

3.58 (1.01)

3.47 (0.90)

3.53 (1.05)

2.87 (0.77)

3.67 (1.08)

4.02 (1.01)

3.52 (0.91)

 

TT

3.56 (0.96)

3.77** (0.99)

3.58 (0.93)

3.68** (1.00)

2.59** (0.77)

3.62 (0.98)

4.22** (0.96)

3.49 (0.92)

 

Total

3.38 (0.91)

3.58 (0.97)

3.55 (0.96)

3.54 (0.90)

2.84 (0.81)

3.67 (1.02)

3.98 (1.02)

3.51 (0.98)

HDL-Chol, mmol/l

CC

1.21 (0.38)

1.37 (0.43)

1.42 (0.33)

1.35 (0.35)

1.40 (0.30)

1.51 (0.31)

1.55 (0.30)

1.49 (0.39)

 

CT

1.32 (0.37)

1.39 (0.34)

1.36 (0.33)

1.38 (0.42)

1.47 (0.33)

1.49 (0.36)

1.48 (0.34)

1.48 (0.45)

 

TT

1.21 (0.43)

1.35 (0.40)

1.52* (0.35)

1.36 (0.37)

1.50 (0.32)

1.47 (0.39)

1.46 (0.06)

1.48 (0.39)

 

Total

1.27 (0.39)

1.38 (0.49)

1.42 (0.36)

1.36 (0.30)

1.45 (0.32)

1.49 (0.26)

1.50 (0.38)

1.48 (0.33)

TG, mmol/l

CC

1.68 (0.54)

1.51 (0.86)

1.29 (0.59)

1.50 (0.70)

1.33 (0.49)

1.44 (0.61)

1.50 (0.67)

1.42 (0.59)

 

CT

1.40*** (0.56)

1.46 (0.85)

1.32 (0.57)

1.43 (0.84)

1.36 (0.44)

1.47 (0.72)

1.52 (0.67)

1.45 (0.68)

 

TT

1.70* (0.58)

1.57 (0.80)

1.43 (0.58)

1.57* (0.75)

1.29 (0.45)

1.50 (0.69)

1.61 (0.66)

1.47 (0.66)

 

Total

1.54 (0.52)

1.50 (0.73)

1.33 (0.60)

1.48 (0.60)

1.34 (0.48)

1.46 (0.77)

1.54 (0.64)

1.44 (0.66)

  1. Data adjusted by age and body mass index (BMI) in each age group. Abbreviations: TChol – total cholesterol; LDL-Chol – low density lipoprotein cholesterol; HDL-Chol – high density lipoprotein cholesterol; TG – triglyceride.
  2. * - means significantly different (p <0.05) between TT and CT.
  3. ** - means significantly different (p < 0.05) between TT and CC.
  4. *** - means significantly different (p < 0.05) between CT and CC.