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Table 2 Independent associations between risk factors and desaturase activities in 5 lipid pools in regression models that also included African Caribbean ethnicity and Asian Indian ethnicity (partial correlation coefficients)

From: Ethnic variation in the activity of lipid desaturases and their relationships with cardiovascular risk factors in control women and an at-risk group with previous gestational diabetes mellitus: a cross-sectional study

  BMI Waist Waist hip ratio Systolic BP Diastolic BP Chol Trig HDL chol Glucose HOMA-IS
Stearoyl-CoA desaturase C16
     FF 0.20† 0.16* 0.00 0.09 0.04 −0.07 0.06 0.00 0.04 0.00
     TG 0.09 0.05 −0.01 0.07 0.04 −0.06 0.09 −0.01 −0.01 0.07
     CE 0.29 § 0.26§ 0.22† 0.07 0.01 0.14 0.39§ −0.10 0.10 −0.03
     PL 0.27 § 0.18* −0.02 0.12 0.06 0.03 0.20† 0.01 0.12 −0.09
Stearoyl-CoA desaturase C18
     FF 0.21† 0.18* 0.06 0.11 0.14 −0.13 0.02 −0.02 0.09 −0.03
     TG −0.11 −0.15* −0.12 −0.01 0.01 −0.08 −0.03 −0.05 −0.03 0.11
     CE −0.07 −0.07 0.09 0.00 −0.05 0.05 0.01 0.01 −0.03 0.14
     PL 0.01 −0.05 −0.08 0.09 0.01 −0.13 −0.17* 0.13 −0.04 0.03
n-6 Δ-6 desaturase
     FF 0.01 0.07 0.04 0.05 0.08 −0.05 0.05 −0.09 −0.02 −0.08
     TG 0.10 0.12 0.12 −0.01 −0.04 0.16* 0.10 0.11 0.04 −0.13
     CE 0.26§ 0.23† 0.12 −0.02 0.01 0.03 0.28§ −0.19† −0.04 −0.12
     PL 0.20† 0.18* 0.14 0.06 −0.10 0.11 0.32§ −0.17* −0.06 0.11
n-6 Δ-5 desaturase
     FF −0.02 −0.01 −0.01 0.00 0.07 0.14 0.12 0.14 0.01 0.03
     TG 0.03 −0.02 −0.08 0.11 0.16* −0.17* −0.35§ 0.13 −0.04 0.25§
     CE −0.12 −0.13 −0.15* 0.15 0.12 0.02 −0.11 0.15* 0.20† 0.04
     PL −0.22† −0.21† −0.21† −0.01 −0.06 −0.16* −0.37§ 0.24† 0.06 0.01
n-3 Δ desaturase
     FF 0.00 0.04 −0.01 −0.07 −0.05 0.06 0.14 −0.02 −0.10 −0.08
     TG 0.14 0.12 0.07 −0.04 0.01 −0.03 −0.08 0.02 −0.08 0.12
     CE 0.05 −0.01 0.13 −0.08 −0.11 0.04 −0.14 0.22† −0.04 −0.08
     PL −0.08 −0.02 0.09 0.02 −0.11 0.09 −0.04 0.16* −0.03 −0.12
African Caribbean 0.24†–0.34 § 0.18*–0.32 § 0.09–0.22† 0.15–0.20* 0.22†–0.27† −0.07–0.04 −0.13–0.11 −0.02–0.08 −0.02–0.07 −0.22†–−0.13
Asian Indian 0.06–0.14* 0.01–0.08 −0.05–0.20† −0.10–−0.01 −0.02–0.03 0.04–0.15* 0.20†–0.40§ −0.34§–−0.21† −0.02–0.02 −0.03–0.07
  1. Abbreviations: TF total fatty acids; FF free fatty acids; TG triglycerides; CE cholesterol esters; PL phospholipids. Significances: * p < 0.05 (borderline); † p < 0.01; § p < 0.001.
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Lipids in Health and Disease

ISSN: 1476-511X