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Figure 4 | Lipids in Health and Disease

Figure 4

From: Effects of soluble epoxide hydrolase inhibitor on the expression of fatty acid synthase in peripheral blood mononuclear cell in patients with acute coronary syndrome

Figure 4

Effects of sEHi on expression levels of FAS and IL-6 mRNA and protein in PBMCs. PBMCs were isolated from peripheral blood of ACS patients. Then, t-AUCB, a kind of sEHi was added to cells of ACS group in various concentrations (0, 10, 50, 100) μmol/L and incubated for 24 hours. a. FAS and IL-6 mRNA were detected by real-time PCR. All the effective data were statistically analyzed by 2-ΔΔCt. b. FAS and IL-6 protein were detected by Western blots. β-actin was the internal control. *P<0.05 compared to the group without sEHi (t-AUCB 0 μmol/L). sEHi: soluble epoxide hydrolase inhibitor; FAS: fatty-acid synthase; PBMCs: peripheral blood mononuclear cells; ACS: acute coronary syndrome.

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Lipids in Health and Disease

ISSN: 1476-511X