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Table 1 Characteristics of the study subjects

From: The combined effects of genetic variation in the SIRT1 gene and dietary intake of n-3 and n-6 polyunsaturated fatty acids on serum LDL-C and HDL-C levels: a population based study

 

Male

Female

P-value

n

707

723

 

Age (years)

53.8 ± 5.2

53.0 ± 5.1

0.075

BMI (kg/m2)

23.5 ± 2.9

22.2 ± 3.1

<0.0001

Total Cholesterol (mg/dl)

209.9 ± 31.4

217.7 ± 31.4

<0.0001

LDL-Cholesterol (mg/dl)

130.4 ± 29.8

131.9 ± 30.0

0.38

HDL-Cholesterol (mg/dl)

57.0 ± 16.3

71.5 ± 17.1

<0.0001

Triglyceride (mg/dl)

137.8 ± 102.5

86.8 ± 45.8

<0.0001*

glucose (mg/dl)

99.5 ± 15.4

92.7 ± 10.9

<0.0001*

HbA1c (%)

5.3 ± 0.59

5.1 ± 0.44

<0.0001

Smokers (%)

42.5

8.4

<0.0001

Dietary intakes

   

Energy (kcal/day)

2106.5 ± 567.0

1615.5 ± 414.9

<0.0001

Total fat (%energy)

25.9 ± 6.0

28.2 ± 5.7

<0.0001

Carbohydrate (%energy)

57.1 ± 7.8

56.0 ± 7.0

0.012

SFA (%energy)

6.5 ± 1.8

7.6 ± 2.0

<0.0001

PUFA (%energy)

6.7 ± 1.7

7.0 ± 1.6

0.0019

n-6 PUFA (%energy)

5.4 ± 1.5

5.7 ± 1.4

0.0004

n-3 PUFA (%energy)

1.5 ± 0.49

1.5 ± 0.44

0.42

Alcohol (g/day)

28.7 ± 31.6

6.5 ± 14.6

<0.0001

  1. BMI body mass index, HbA1c hemoglobin A1c, SFA saturated fatty acid, PUFA polyunsaturated fatty acid.
  2. Data are expressed as mean ± SD or percentage.
  3. P-values were calculated by t-test or χ2 test.
  4. The subject numbers whose data for LDL-Cholesterol, HbA1c, and dietary intake available are 1430, 1408, and 1248, respectively.
  5. *Statistical tests for triglyceride and glucose levels were calculated on log-transformed values.