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Table 2 Lipid and metabolic changes from baseline to 90 days of combination antiretroviral therapy

From: Cardiometabolic risk factors among HIV patients on antiretroviral therapy

Variable

Baseline (n = 118)

End (n = 118)

P* for change

HDL-cholesterol, mmol/L

0.72 [0.52, 1.09]

1.34 [1.09, 1.70]

< 0.001

LDL-cholesterol, mmol/L

2.12 ± 0.75

2.28 ± 0.59

0.02

Total cholesterol, mmol/L

3.56 ± 0.83

4.09 ± 0.86

< 0.001

Triglycerides, mmol/L

1.02 [0.85, 1.37]

1.03 [0.79, 1.37]

0.36

TC:HDL-c ratio

4.77 [3.51, 6.30]

2.93 [2.38, 3.69]

< 0.001

Insulin, μU/mL

3.00 [1.90, 5.40]

6.40 [3.40, 12.50]

< 0.001

Glucose, mmol/L

3.80 [3.40, 4.10]

4.00 [3.40, 4.50]

0.048

HOMA-IR

0.51 [0.30, 0.98]

1.12 [0.61, 2.21]

< 0.001

BMI, kg/m2

20.15 ± 2.70

20.89 ± 2.92

< 0.001

Weight, kg

54.9 ± 8.7

56.8 ± 9.0

< 0.001

  1. Values are reported as mean ± standard deviation or median [25th percentile, 75th percentile].
  2. * P-values obtained from paired t-tests or Wilcoxon Signed rank tests.