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Table 2 Lipid and metabolic changes from baseline to 90 days of combination antiretroviral therapy

From: Cardiometabolic risk factors among HIV patients on antiretroviral therapy

Variable Baseline (n = 118) End (n = 118) P* for change
HDL-cholesterol, mmol/L 0.72 [0.52, 1.09] 1.34 [1.09, 1.70] < 0.001
LDL-cholesterol, mmol/L 2.12 ± 0.75 2.28 ± 0.59 0.02
Total cholesterol, mmol/L 3.56 ± 0.83 4.09 ± 0.86 < 0.001
Triglycerides, mmol/L 1.02 [0.85, 1.37] 1.03 [0.79, 1.37] 0.36
TC:HDL-c ratio 4.77 [3.51, 6.30] 2.93 [2.38, 3.69] < 0.001
Insulin, μU/mL 3.00 [1.90, 5.40] 6.40 [3.40, 12.50] < 0.001
Glucose, mmol/L 3.80 [3.40, 4.10] 4.00 [3.40, 4.50] 0.048
HOMA-IR 0.51 [0.30, 0.98] 1.12 [0.61, 2.21] < 0.001
BMI, kg/m2 20.15 ± 2.70 20.89 ± 2.92 < 0.001
Weight, kg 54.9 ± 8.7 56.8 ± 9.0 < 0.001
  1. Values are reported as mean ± standard deviation or median [25th percentile, 75th percentile].
  2. * P-values obtained from paired t-tests or Wilcoxon Signed rank tests.