A new ratio for better predicting future death/myocardial infarction than standard lipid measurements in women >50 years undergoing coronary angiography: the apolipoprotein A1 remnant ratio (Apo A1/ [VLDL3+IDL])

May, Heidi T; Nelson, John R; Kulkarni, Krishnaji R; Anderson, Jeffrey L; Horne, Benjamin D; Bair, Tami L; Muhlestein, Joseph B

doi:10.1186/1476-511X-12-55

Lipids in Health and Disease

Table 3 Multivariable association of tertiles of lipoprotein and lipid parameters for 1 and 3 year Death/MI

From: A new ratio for better predicting future death/myocardial infarction than standard lipid measurements in women >50 years undergoing coronary angiography: the apolipoprotein A1 remnant ratio (Apo A1/ [VLDL₃+IDL])

Outcome	1 year death/MI	3 year death/MI
Apo A1-C/(VLDL ₃ -C+IDL-C)
Tertile 1 vs. Tertile 3	HR=2.14, p=0.03	HR=2.33, p=0.003
Tertile 2 vs. Tertile 3	HR=1.52, p=0.27	HR=1.95, p=0.02
Apo A1
Tertile 1 vs. Tertile 3	HR=1.81, p=0.07	HR=1.80, p=0.02
Tertile 2 vs. Tertile 3	HR=0.77, p=0.49	HR=0.72, p=0.27
Apo B
Tertile 2 vs. Tertile 1	HR=1.70, p=0.11	HR=1.18, p=0.49
Tertile 3 vs. Tertile 1	HR=1.34 p=0.42	HR=0.96, p=0.89
Apo B/A1 Ratio
Tertile 2 vs. Tertile 1	HR=0.76, p=0.48	HR=0.94, p=0.82
Tertile 3 vs. Tertile 1	HR=1.97, p=0.03	HR=1.83, p=0.01
HDL-C
Tertile 1 vs. Tertile 3	HR=0.96, p=0.89	HR=1.19, p=0.48
Tertile 2 vs. Tertile 3	HR=0.72, p=0.36	HR=0.62, p=0.10
Triglycerides
Tertile 2 vs. Tertile 1	HR=1.56, p=0.20	HR=1.48, p=0.14
Tertile 3 vs. Tertile 1	HR=1.19, p=0.65	HR=1.26, p=0.40
LDL-C
Tertile 2 vs. Tertile 1	HR=0.88, p=0.73	HR=0.74, p=0.26
Tertile 3 vs. Tertile 1	HR=1.35, p=0.38	HR=1.09, p=0.74
Non-HDL-C
Tertile 2 vs. Tertile 1	HR=1.19, p=0.62	HR=1.11, p=0.69
Tertile 3 vs. Tertile 1	HR=1.30, p=0.47	HR=1.002, p=0.99
Triglycerides/HDL-C Ratio
Tertile 2 vs. Tertile 1	HR=1.10, p=0.76	HR=1.53, p=0.08
Tertile 3 vs. Tertile 1	HR=0.90, p=0.77	HR=1.20, p=0.50
VLDL ₃ -C+IDL-C
Tertile 2 vs. Tertile 1	HR=1.31, p=0.45	HR=1.46, p=0.14
Tertile 3 vs. Tertile 1	HR=1.90, p=0.05	HR=1.55, p=0.09
Total Cholesterol/HDL-C Ratio
Tertile 2 vs. Tertile 1	HR=0.89, p=0.72	HR=0.96, p=0.87
Tertile 3 vs. Tertile 1	HR=0.91, p=0.77	HR=1.27, p=0.33
HDL-C/(VLDL ₃ -C+IDL-C)
Tertile 1 vs. Tertile 3	HR=1.70, p=0.10	HR=2.07, p=0.004
Tertile 2 vs. Tertile 3	HR=0.97, p=0.92	HR=1.35, p=0.27
LDL-C/HDL-C
Tertile 2 vs. Tertile 1	HR=0.60, p=0.15	HR=0.89, p=0.64
Tertile 3 vs. Tertile 1	HR=0.96, p=0.90	HR=1.15, p=0.57

Apo: apolipoprotein; HDL-C: high density lipoprotein cholesterol; IDL-C: intermediate density lipoprotein cholesterol; LDL-C: low density lipoprotein cholesterol; VLDL-C: very low density lipoprotein₃ cholesterol.

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ISSN: 1476-511X

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