Consequence of COX-2 expression. Basal release of prostacyclin (Panel A) or PGE2 (Panel B) in VSMC from DP and non-DP. Bar graph shows the mean±SEM of n = 4 patients, **P < 0.01. Panel C: Bivariate correlation between serum MMP-9 levels and COX-2 expression in internal mammary arteries. Analysis was performed by Pearson correlation.